| 冬虫夏草对糖尿病肾病大鼠糖脂代谢紊乱的影响 |
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| 引用本文： | 宗灿华.冬虫夏草对糖尿病肾病大鼠糖脂代谢紊乱的影响[J].牡丹江医学院学报,2008,29(3):8-10. |
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| 作者姓名： | 宗灿华 |
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| 作者单位： | 牡丹江医学院生物化学与分子生物学教研室,黑龙江,牡丹江,157011 |
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| 摘 要： | 目的:探讨冬虫夏草对糖尿病肾病大鼠糖脂代谢紊乱的影响.方法:50只Wistar大鼠,随机选取10只作为正常对照组,余下的40只建立糖尿病肾病(DN)大鼠模型后,将DN大鼠随机分为模型对照组、冬虫夏草高、低剂量组,每组10只.用药8周后,测定各组大鼠血糖、血肌酐、尿蛋白排泄量、血脂的变化.结果:与糖尿病肾病模型组比较,冬虫夏草高、低剂量组血肌酐、尿蛋白排泄量、总胆固醇、甘油三酯、低密度脂蛋白均显著降低(P<0.01-0.05),高密度脂蛋白虽有所升高,但差异不显著.结论:冬虫夏草防治糖尿病肾病的机制之一是改善糖脂代谢紊乱.
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| 关 键 词： | 冬虫夏草 糖尿病肾病 血糖 血脂 |
EFFECT OF CORDYCEPS SINENSIS ON METABOLISM OF BLOOD GLUCOSE AND LIPID IN DIABETIC NEPHROPATHY RATS |
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| Zong Canhua.EFFECT OF CORDYCEPS SINENSIS ON METABOLISM OF BLOOD GLUCOSE AND LIPID IN DIABETIC NEPHROPATHY RATS[J].Journal of Mudanjiang Medical College,2008,29(3):8-10. |
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| Authors: | Zong Canhua |
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| Institution: | Zong Canhua (Department of Biochemistry , Molecular Biology,Mudanjiang Medical College,Mudanjiang Heilongjiang 157011) |
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| Abstract: | Objective:To observe the influence of cordyceps sinensis on metabolism of blood glucose and lipid in diabetic nephropathy rats.Methods:Normal control group was established in 10 randomly selected from 50 Wistar rats.Another 40 rats were used to establish diabetic nephropathy models.Diabetic nephropathy model rats were randomly divided into 3 groups and there were 10 rats in each group:model group,heavy dose of cordyceps sinensis treatment group and low dose of cordyceps sinensis treatment group.After 8 week... |
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| Keywords: | Cordyceps sinensis diabetic nephropathy blood glucose blood lipid |
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