| 调肺汤联合化疗治疗晚期非小细胞肺癌的临床研究 |
| |
| 引用本文： | 束家和,周荣耀,刘宏杰.调肺汤联合化疗治疗晚期非小细胞肺癌的临床研究[J].中国中医药科技,2011,18(4):275-277,271. |
| |
| 作者姓名： | 束家和 周荣耀 刘宏杰 |
| |
| 作者单位： | 上海中医药大学附属曙光医院·上海200021 |
| |
| 摘 要： | 目的：观察调肺汤联合化疗治疗晚期非小细胞肺癌的有效性、安全性、及其对VEGF等指标的影响。方法：120例晚期非小细胞肺癌患者,随机分成两组,调肺汤联合化疗治疗组60例,对照组60例（化疗）,治疗2个疗程后,评定疗效,并进行生存质量评估,同时检测免疫功能指标及VEGF水平。结果：治疗组和对照组实体瘤近期有效率分别为48.33%、35.00%,组间差异有统计学意义（P〈0.05）;治疗组VEGF水平下降程度优于对照组,组间差异有统计学意义（P〈0.05）;两组在生活质量（KPS）及免疫指标（NK细胞、T细胞亚群）的改善、临床获益率、中位疾病进展时间、中位生存时间、一年生存率等方面比较,治疗组均优于对照组,差异均有统计学意义（P〈0.05）;两组在外周血血红蛋白、白细胞、血小板下降等不良反应发生方面比较,差异有统计学意义（P〈0.05）;而在其他不良反应发生方面,差异无统计学意义（P〉0.05）。结论：调肺汤能有效地治疗晚期非小细胞肺癌,改善生活质量,提高免疫指标,延长生存期,下调VEGF水平,并减少治疗中的不良反应。
|
| 关 键 词： | 肺肿瘤/中西医结合疗法 @调肺汤/治疗应用 人类 |
CLINICAL STUDY ON ADVANCED NON-SMALL CELL LUNG CANCER TREATED WITH TIAOFEI DECOCTION COMBINING WITH CHEMOTHERAPY |
| |
| SHU Jiahe,ZHOU Rongyao,LIU Hongjie.CLINICAL STUDY ON ADVANCED NON-SMALL CELL LUNG CANCER TREATED WITH TIAOFEI DECOCTION COMBINING WITH CHEMOTHERAPY[J].Chinese Journal of Traditional Medical Science and Technology,2011,18(4):275-277,271. |
| |
| Authors: | SHU Jiahe ZHOU Rongyao LIU Hongjie |
| |
| Institution: | SHU Jiahe,ZHOU Rongyao,LIU Hongjie(Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200021) |
| |
| Abstract: | Objective:To observe the efficacy and safety of tiaofei decoction combining with chemotherapy in tne treatment of advanced non-small cell lung cancer(NSCLC) and the effect on VEGF expression.Methods:120 cases with NSCLC were divided into two groups,treated group was given tiaofei decoction combining with chemotherapy,control group was simply given chemotherapy,assessed the curative effect after two treatment courses,evaluated the quality of life,determined the changes of immunologic indexes and VEGF express... |
| |
| Keywords: | |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
