| 液压脑损伤大鼠行为学和脑电图的研究 |
| |
| 引用本文： | 李雪峰,刘绍明,郑刚,窦彩绘,李建. 液压脑损伤大鼠行为学和脑电图的研究[J]. 中华神经外科杂志, 2006, 25(1): 560-563. DOI: 10.3760/cma.j.issn.1001-2346.2009.06.029 |
| |
| 作者姓名： | 李雪峰 刘绍明 郑刚 窦彩绘 李建 |
| |
| 作者单位： | 河南焦煤集团中央医院神经外科;兰州军区乌鲁木齐总医院神经外科,830000; |
| |
| 基金项目： | 中国人民解放军兰州军区医药卫生科研基金资助项目 |
| |
| 摘 要： | Objective To investigate the electroencephalogram and ethology in the rat with fluid percussion brain injury and approach its research value in the post traumatic epilepsy. Methods The change of ethology and electroencephalogram of rat in the three months after fluid percussion brain injury were observed and recorded. Results Among the survival 31 rats, there were 11 rats that appeared epilepsy. Epileptic seizure manifestation principally appeared as facial spasm, nod motion, and next limbs convulsion and turnover upspring, et al. The highest epileptic incidence rate appeared in 2 months after lateral fluid percussion brain injury. There were obvious epileptic discharges on the electroencephalogram of epileptic rats and higher wave amplitude and quicker frequency on the lead of 1～5 on the electroencephalogram of some no epileptic rats. Conclusions Post traumatic epilepsy after lateral fluid percussion brain injury in rat is similar with clinical post traumatic epilepsy. It has more research value than the other pest traumatic epileptic animal model.
|
| 关 键 词： | 液压脑损伤 外伤后癫痫 脑电描记术 动物模型 |
Study on electroencephalogram and ethology in the rat with fluid percussion brain injury |
| |
| Abstract: | |
| |
| Keywords: | Fluid percussion brain injuryPost traumatic epilepsyElectroencephalographyAnimal model |
|
|
