应用人巨细胞病毒-核酸扩增反应对复方黄芪颗粒治疗感染人巨细胞病毒小鼠的疗效评价

目的应用人巨细胞病毒-核酸扩增(HCMV-PCR)反应探讨中药复方黄芪颗粒对感染HCMV小鼠治疗作用。方法用小鼠尾静脉染毒法建立HCMV全身获得性感染模型,并用复方黄芪颗粒给小鼠灌胃治疗,然后应用HCMV-PCR反应测定其内脏HCMV-DNA阳性率。结果复方黄芪颗粒42.0,21.0 g/kg组HCMV-DNA阳性率明显低于模型组(P<0.05)。结论复方黄芪颗粒对感染HCMV小鼠有一定的治疗作用。

Evaluation of Curative Effect of Radix Astragali Grain Small Rat ou treating Human Cytomegalovirus Infection in Mice by the HCMV-PCR Respond

ObjectiveTo study the curative effect of radix astragali grain of Chinese herbal medicine compound prescribe on right infection HCMV by HCMV-PCR respond.MethodsDye the poison method to establish the HCMV whole body to acquire with vein of mice tail sexy dye the model,and counteract the radix astragali grain of compound prescribe to the mice respectively the treatment,then apply the HCMV-PCR to respond to measurese the male rate of HCMV-DNA of its internal organs.Results Radix astragali grain of compound prescribe 42.0 g/ kg,21.0 g/ kg male rate of HCMV-DNA of setses obviously arrive in the model set(P<0.05).ConclusionThe radix astragali grain of compound prescribe treatment infection HCMV mice had certainly function.