睡眠呼吸暂停综合征116例临床特点与年龄及肥胖的相关性分析

目的: 探讨睡眠呼吸暂停综合征(sleep apnea syndrome,SAS)患者的临床特点与年龄及肥胖的相关性。方法: 采用多导睡眠监测仪(PSG)对116例SAS患者进行睡眠监测,按体重指数(BMI)分为肥胖组(57例)与非肥胖组(59例),按年龄分为老年组(26例)与中青年组(90例),分析对应组间SAS患者的临床特点。结果: 呼吸暂停低通气指数(AHI)、最长呼吸暂停持续时间(LAT)、平均呼吸暂停持续时间(MAT)肥胖组较非肥胖组高,最低血氧饱和度(LSaO₂)、平均血氧饱和度(MSaO₂)肥胖组较非肥胖组低,差异均有显著性(P<0.005-P<0.001)。颈围、BMI老年组较中青年组低,差异均有显著性(P<0.01-P<0.005);AHI、LAT老年组较中青年组低,ISaO₂、MSaO₂老年组较中青年组高,差异均有显著性(P<0.05~P<0.005)。结论: 肥胖组SAS患者严重程度较非肥胖组SAS患者重,老年组SAS患者严重程度较中青年组SAS患者轻.

Correlation of sleep apnea syndrome with the age and body weight:A report of 116 cases

Objective:To investigate the correlation between sleep apnea syndrome(SAS) and the age and body weight.Methods:One hundred and sixteen patients with SAS were diagnosed by polysomnography(PSG) and classified into the aged group and middle-aged group,the obesity group and non-obesity group.Results:The apnea hypopnea index(AHI),longest apnea time(LAT) and mean apnea time(MAT) of the obesity group were significantly higher than those of the non-obesity group,and the index of lowest arterial O_2 saturation(LSaO_2) and mean arterial O_2 saturation(MSaO_2) were lower than those of the non-obesity group(P<0.005 to P<0.001).Both the body mass index(BMI) and neck circumference were lower in the aged group than in the middle-aged group(P<0.01 to P<0.005);AHI,LAT and MAT were lower in the aged group comparatively.LSaO_2 and MSaO_2 were significantly higher in the aged group than those in the middle-aged group(P<0.05 to P<0.005).Conclusions:The severity of SAS is positively correlated with body weight and negatively correlated with age.