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Antibiotic-exposed patients with non-small-cell lung cancer preserve efficacy outcomes following first-line chemo-immunotherapy
Affiliation:1. Department of Biotechnology and Applied Clinical Sciences, University of L''Aquila, L''Aquila, Italy;2. Division of Cancer, Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital, London, UK;3. Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA;4. Université Paris-Saclay, Institut Gustave Roussy, Inserm, Biomarqueurs Prédictifs et Nouvelles Stratégies Thérapeutiques en Oncologie, Villejuif, France;5. Cancer Medicine Department, Gustave Roussy, Villejuif, France;6. Cancer Division, University College London Hospitals, London, UK;7. Medical Oncology Department, Hospital de la Santa Creu I Sant Pau, Barcelona, Spain;8. Department of Medical Oncology, Royal Marsden Hospital, London, UK;9. Department of Twin Research and Genetic Epidemiology, St Thomas''s Hospital, King''s College London, London, UK;10. Department of Experimental, Diagnostic and Specialty Medicine, S. Orsola-Malpighi University Hospital, Alma Mater Studiorum University of Bologna, Bologna, Italy;11. Department of Medical Oncology, Hospital Clinic, Barcelona, Spain;12. Department of Pathology, Cliniques universitaires Saint-Luc, Brussels, Belgium;13. Institut de Recherche Expérimentale et Clinique (IREC), Pôle de Pneumologie, ORL et Dermatologie (PNEU), Université catholique de Louvain (UCLouvain), Brussels, Belgium;14. University Paris-Saclay, School of Medicine, Villejuif, France;15. Division of Oncology, Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy
Abstract:
Keywords:antibiotics  pembrolizumab  chemotherapy  immune checkpoint inhibitors  non-small-cell lung cancer  predictive factors
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