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Continuous versus intermittent extended adjuvant letrozole for breast cancer: final results of randomized phase III SOLE (Study of Letrozole Extension) and SOLE Estrogen Substudy
Affiliation:1. International Breast Cancer Study Group, Bern, Switzerland;2. Medical Oncology Department, CHU Liège, Liège University, Liège, Belgium;3. International Breast Cancer Study Group Statistical Center, Division of Biostatistics, Dana-Farber Cancer Institute, Boston, USA;4. Breast Cancer Trials-Australia and New Zealand, University of Newcastle, Callaghan, Australia;5. Box Hill and Maroondah Hospitals, Monash University, Clayton, Australia;6. Division of Medical Oncology, Cancer Center, Lucerne Cantonal Hospital, Lucerne, Switzerland;7. Faculty of Medicine, University of Bern, Bern, Switzerland;8. Department of Oncology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden;9. Gynecologic Oncology and Multidisciplinary Breast Center, University Hospitals UZ-Leuven, KU Leuven, Leuven, Belgium;10. Department of Medical Oncology and Clinical Pharmacology “B”, National Institute of Oncology, Budapest, Hungary;11. Montlégia Hospital, Liège, Belgium;12. ASST Spedali Civili di Brescia, Brescia, Italy;13. The Tweed Hospital, Griffith University Gold Coast, Tweed Heads, Australia;14. Danish Breast Cancer Group and Rigshospitalet, Copenhagen, Denmark;15. Scottish Cancer Trials Breast Group and Division of Surgical Oncology, Baylor College of Medicine, Houston, USA;16. German Breast Group Forschungs GmbH, Neu-Isenburg, Germany;17. SOLTI Group and Fundación Instituto Valenciano de Oncologia, Valencia, Spain;18. Japan Breast Cancer Research Group and Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, Japan;19. Austrian Breast & Colorectal Cancer Study Group and Department of Obstetrics and Gynecology, Medical University Innsbruck, Innsbruck, Austria;20. Chilean Cooperative Group for Oncologic Research (GOCCHI), Providencia, Santiago, Chile;21. Cancer Trials Ireland, Dublin, Ireland;22. University College Cork, Cork University Hospital, Cork, Ireland;23. Université Libre de Bruxelles, Institut Jules Bordet, Brussels, Belgium;24. Swiss Group for Clinical Cancer Research SAKK, Bern, Switzerland;25. Breast Center St. Gallen, St. Gallen, Switzerland;26. Faculty of Medicine, University of Basel, Basel, Switzerland;27. Harvard Medical School, Boston, USA;28. Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA;29. Department of Medical Oncology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland;30. Department of Pathology, University of Milan, Milan, Italy;31. IEO European Institute of Oncology IRCCS, Milan, Italy;32. Harvard TH Chan School of Public Health, Boston, USA;33. Frontier Science Foundation, Boston, USA;34. NHMRC Clinical Trials Centre, University of Sydney, Sydney, Australia;35. Peter MacCallum Cancer Center, University of Melbourne, Melbourne, Australia;36. IEO European Institute of Oncology, IRCCS, Milan, Italy;37. Division of Medical Senology, IEO, European Institute of Oncology, IRCCS, Milan, Italy
Abstract:
Keywords:breast cancer  endocrine therapy  letrozole  estrogen
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