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Laparoscopic and Robotic Surgery for Endometrial and Cervical Cancer
Affiliation:1. Academic Department of Gynaecological Oncology, Royal Surrey NHS Foundation Trust, Guildford, Surrey, UK;2. Department of Obstetrics & Gynecology, Command Hospital, Kolkata, West Bengal, India;1. School of Medicine, International Medical University, Kuala Lumpur, Malaysia;2. Department of Radiology, Wirral University Teaching Hospital NHS Foundation Trust, Wirral, UK;3. Department of Clinical Oncology, The Clatterbridge Cancer Centre, Clatterbridge Cancer Centre NHS Foundation Trust, Wirral, UK;4. Department of Clinical Oncology, Leeds Cancer Centre, St James''s Institute of Oncology, Leeds, UK;1. Mount Vernon Cancer Centre, Northwood, UK;2. Division of Cancer Sciences, University of Manchester, Manchester, UK;1. Department of Gynecological Oncology, Oslo University Hospital, The Norwegian Radium Hospital, Oslo, Norway;2. Department of Gynecologic Oncology, University of North Carolina, Chapel Hill, NC, USA;3. Department of Gynecologic Oncology, Florida Hospital Cancer Institute, Orlando, FL, USA;4. National Advisory Unit for Late Effects after Cancer Treatment, Oslo University Hospital, The Norwegian Radium Hospital, Oslo, Norway;5. Faculty of Medicine, University of Oslo, Oslo, Norway;6. Division of Gynecological Oncology, University of Cincinnati Medical Center, Cincinnati, OH, USA;1. Gynecology Department, European Institute of Oncology, Milan, Italy;2. Gynecology Department, Instituto Valenciano de Oncología, Valencia, Spain;1. Department of Gynaecology and Obstetrics, Odense University Hospital, J. B. Winsløws Vej 4, 5000 Odense C, Denmark;2. OPEN, Odense Patient Data Explorative Network, Odense University Hospital, B. Winsløws Vej 9 A, 5000 Odense C, Denmark;3. Department of Clinical Health, Faculty of Health Sciences, Clinical Institute, University of Southern Denmark, J.B. Winsløws Vej 19, 5000 Odense C, Denmark;4. Department of Pelvic Cancer, Karolinska University Hospital and Karolinska Institute, SE-171 77 Stockholm, Sweden;5. Centre for Clinical Epidemiology, Odense University Hospital, Kløvervænget 30, 5000 Odense, Denmark;6. Research Unit of Clinical Epidemiology, Institute of Clinical Research, University of Southern Denmark, Sdr. Boulevard 29, 5000 Odense C, Denmark;7. Danish Centre for Health Economics (DaCHE), Department of Public Health, University of Southern Denmark, J.B. Winsløws Vej 9B, 1st Floor, 5000 Odense C, Denmark;1. Department of Gynecologic Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China;2. Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China;3. Department of Anesthesiology and Pain Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Abstract:Minimally invasive surgery (MIS) has many benefits, in the form of reduced postoperative morbidity, improved recovery and reduced inpatient stay. It is imperative, however, when new techniques are adopted, in the context of treating oncology patients, that the oncological efficacy and safety are established rigorously rather than assumed based on first principles. Here we have attempted to provide a comprehensive review of all the contentious and topical themes surrounding the use of MIS in the treatment of endometrial and cervix cancer following a thorough review of the literature. On the topic of endometrial cancer, we cover the role of laparoscopy in both early and advanced disease, together with the role and unique benefits of robotic surgery. The surgical challenge of patients with a raised body mass index and the frail and elderly are discussed and finally the role of sentinel lymph node assessment. For cervical cancer, the role of MIS for staging and primary treatment is covered, together with the interesting and highly specialist topics of fertility-sparing treatment, ovarian transposition and the live birth rate associated with this. We end with a discussion on the evidence surrounding the role of adjuvant hysterectomy following radical chemoradiation and pelvic exenteration for recurrent cervical cancer. MIS is the standard of care for endometrial cancer. The future of MIS for cervix cancer, however, remains uncertain. Current recommendations, based on the available evidence, are that the open approach should be considered the gold standard for the surgical management of early cervical cancer and that MIS should only be adopted in the context of research. Careful counselling of patients on the current evidence, discussing in detail the risks and benefits to enable them to make an informed choice, remains paramount.
Keywords:Cervical cancer  endometrial cancer  fertility-sparing surgery  laparoscopic surgery  pelvic exenteration  robotic surgery
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