Quality of life of Japanese elderly oral cancer patients during the perioperative period |
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Institution: | 1. Department of Oral and Maxillofacial Surgery, Tokai University School of Medicine, Isehara, Kanagawa, Japan;2. Department of Clinical Technology, Medical Technology Support Division, Tokai University Hospital, Isehara, Kanagawa, Japan;3. Department of Radiation Oncology, Tokai University School of Medicine, Isehara, Kanagawa, Japan;1. Department of Dentistry and Oral Surgery, Tokyo Metropolitan Tama Medical Center, Fuchu-shi, Tokyo, Japan;2. Department of Dentistry and Oral Surgery, Tokyo Metropolitan Bokutoh Hospital, Sumida-ku, Tokyo, Japan;3. Department of Stomatology, Tokyo Metropolitan Ohtsuka Hospital, Toshima-ku, Tokyo, Japan;1. Section of Plastic Surgery, Department of Surgery, Yale University School of Medicine, New Haven, CT, USA;2. Division of Plastic and Reconstructive Surgery, Riley Children’s Hospital, Indiana University School of Medicine, Indianapolis, IN, USA;1. Instituto Português da Face, Lisboa, Portugal;2. Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal;1. Araçatuba School of Dentistry – UNESP, São Paulo, Brazil;2. Bauru School of Dentistry, University of São Paulo – USP, São Paulo, Brazil;3. Department of Diagnosis and Surgery, Araçatuba School of Dentistry – UNESP, São Paulo, Brazil |
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Abstract: | Japan’s aging society has an increasing incidence of oral cancer. This study investigated perioperative changes in quality of life (QoL) among 172 oral cancer patients (elderly ≥75 years vs non-elderly <75 years), pre-treatment, at treatment completion, and at 1, 3, and 6 months post-treatment, using the following Functional Assessment of Cancer Therapy – Head and Neck (FACT-H&N) subscales: physical well-being (PWB), social/family well-being (SWB), emotional well-being (EWB), functional well-being (FWB), additional head- and neck-specific concerns (H&N). SWB (P = 0.026), H&N (P = 0.024), and total FACT-H&N (P = 0.009) scores were significantly lower in the elderly group than in the non-elderly group at 6 months post-treatment, especially for mastication items (H&N1, P = 0.047; H&N11, P = 0.004), but not for swallowing items (H&N5 and H&N7, both P > 0.05). PWB (P = 0.004), EWB (P < 0.001), and FWB (P = 0.022) scores in the non-elderly group were significantly higher at 6 months post-treatment than before treatment. In the elderly group, no subscale showed a better score at 6 months post-treatment. Post-treatment QoL in elderly oral cancer patients did not improve, unlike in non-elderly patients. |
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Keywords: | elderly head and neck oral cancer patient- reported outcomes perioperative period quality of life |
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