143例妊娠期梅毒患者妊娠结局及婴幼儿结局研究

Pregnancy and infant outcome of 143 pregnant women infected by syphilis in baoshan district of Shanghai

Objective?To improve the management quality of syphilis during pregnancy in the region. Methods?Data of pregnant women with syphilis infection were collected in Baoshan District of Shanghai from Jan 2013 to Dec 2019. According to the titer classification of rapid plasma regain (RPR) of the first medical visit, all the pregnant women were divided into high titer group and low titer group, and their pregnancy and infant outcome were analyzed. According to the treatment, all the cases were divided into standard treatment group and non-standard treatment group, to analyze the outcome of pregnancy and infants. Results?A total of 143 cases of pregnant women infected with syphilis were collected. The prevalence was 0.23%. Their average age was (29.71±5.52) years old. Only 36.36% of them were Shanghai residents. The education level of the patients showed that 42.66% of all were lower than junior high school, 35.66% were senior high school, 21.68% were Bachelor`s degree or more. The prevalence of pregnant women infected with syphilis were rising during the seven years (P<0.05).The prevalence of obstetric complications of the high titer group was higher than the low titer group (P<0.05). The prevalence of obstetric complications of the standard treatment group was lower than the non-standard treatment group (P<0.05). Conclusion?It should be strengthen that the quality of management and follow-up of pregnant women with syphilis infection and their infants.