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同期整合加量调强放疗在食管癌中的应用进展
引用本文:王澜,王亚敏,刘丽虹,刘树堂,韩春,于金明. 同期整合加量调强放疗在食管癌中的应用进展[J]. 中华放射肿瘤学杂志, 2021, 30(11): 1216-1220. DOI: 10.3760/cma.j.cn113030-20210120-00035
作者姓名:王澜  王亚敏  刘丽虹  刘树堂  韩春  于金明
作者单位:河北医科大学第四医院放疗科,石家庄 050011; 山东省肿瘤防治研究院(山东省肿瘤医院) 山东第一医科大学(山东省医学科学院)放疗科,济南 250117
基金项目:国家重点研发计划项目(2018YFC1313203);国家卫生计生委医院管理研究所项目(WJWYGS-201816)
摘    要:近年非常规分割放疗在多个系统肿瘤的治疗中日益体现出优势。同期整合加量调强放疗(SIB-IMRT)可以在一次照射过程中将不同的分割剂量传递至不同区域,实现在不增加正常组织受量前提下给予高危区域(GTV)局部追加剂量照射,其剂量学优势已得到学界广泛认可。目前,在食管癌领域SIB-IMRT的局控、生存优势、适应证人群、单次分割整合加量的上限界点仍然不明确,特就该技术在食管癌中的应用予以综述。

关 键 词:食管肿瘤/调强放射疗法  同期整合加量  应用进展  
收稿时间:2021-01-20

Research progress on application of simultaneous integrated boost intensity-modulated radiotherapy in esophageal carcinoma
Wang Lan,Wang Yamin,Liu Lihong,Liu Shutang,Han Chun,Yu Jinming. Research progress on application of simultaneous integrated boost intensity-modulated radiotherapy in esophageal carcinoma[J]. Chinese Journal of Radiation Oncology, 2021, 30(11): 1216-1220. DOI: 10.3760/cma.j.cn113030-20210120-00035
Authors:Wang Lan  Wang Yamin  Liu Lihong  Liu Shutang  Han Chun  Yu Jinming
Affiliation:Department of Radiation Oncology, the Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China; Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Shandong, Ji'nan 250017, China
Abstract:In recent years, unconventional fractionated radiotherapy has shown increasing advantages in the treatment of multiple system tumors. Simultaneous integrated boost intensity-modulated radiotherapy (SIB-IMRT) involves the delivery of standard-fraction doses of radiotherapy to different areas, achieving the delivery of higher doses of radiotherapy per fraction to the high-risk gross tumor volume (GTV) without sacrificing the irradiation dose to the normal tissues. The dosimetric advantages of SIB-IMRT have been widely recognized. At present, the local control,survival advantage, indication population and the optimal upper limit of single fraction of SIB-IMRT for esophageal carcinoma are still unclear. This article reviews the application of SIB-IMRT in esophageal carcinoma.
Keywords:Esophageal neoplasm/intensity-modulated radiotherapy  Simultaneous integrated boost  Application progress  
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