| 细胞外囊泡介导的血吸虫?宿主相互作用研究进展 |
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| 引用本文： | 杨瑞冰,李云珍,苏坤华,王立富,李玲.细胞外囊泡介导的血吸虫?宿主相互作用研究进展[J].中国血吸虫病防治杂志,2022,34(3):318. |
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| 作者姓名： | 杨瑞冰 李云珍 苏坤华 王立富 李玲 |
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| 作者单位： | 1 广州金域医学检验中心（广东 广州 510005）；2 中山大学中山医学院寄生虫学教研室（广东 广州 510080） |
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| 基金项目： | 国家自然科学基金青年项目（81902081）；广东省自然科学基金面上项目（2020A1515011573） |
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| 摘 要： | 细胞外囊泡是一类由活细胞分泌的囊泡小体，可以包裹各类生物活性分子远距运输并发挥生物学功能。近年来，随着寄生虫?宿主相互作用研究的深入，细胞外囊泡作为寄生虫远距离运输虫源性分子的载体，可实现对宿主进行跨物种调控而受到广泛关注。在血吸虫感染过程中，成虫及虫卵可以通过分泌细胞外囊泡对宿主进行调控。本文就细胞外囊泡介导的血吸虫?宿主相互作用研究进展作一综述。
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| 关 键 词： | 血吸虫 细胞外囊泡 血吸虫?宿主相互作用 跨物种调控 |
| 收稿时间： | 2022-07-06 |
Advances in studies on schistosome?host interactions mediated by extracellular vesicles |
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| Yang Rui?bing,Li Yun?zhen,Su Kun?hua,Wang Li?fu,Li Ling.Advances in studies on schistosome?host interactions mediated by extracellular vesicles[J].Chinese Journal of Schistosomiasis Control,2022,34(3):318. |
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| Authors: | Yang Rui?bing Li Yun?zhen Su Kun?hua Wang Li?fu Li Ling |
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| Institution: | 1 Guangzhou KingMed Centre for Clinical Laboratory Co., Ltd, Guangzhou, Guangdong 510005, China; 2 Department of Parasitology, Zhongshan School of Medicine, Sun Yat?sen University, Guangzhou, Guangdong 510080, China |
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| Abstract: | Extracellular vesicles (EVs) are minute particles secreted by the cells of living organisms, which can encapsulate various bioactive molecules for long?distance transport to present biological functions. With the recent studies on parasite?host interactions, EVs, as a carrier for long?distance transport of worm?derived molecules, have been paid much attention during the across?species regulation of hosts. During schistosome infections, adult worms and eggs have been found to mediate hosts via secretion of EVs. This review presents the advances in the studies on schistosome?host interactions mediated by EVs. |
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| Keywords: | Schistosome Extracellular vesicle Schistosome?host interaction Cross?species regulation |
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