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| 超声引导下穿刺活检对肺外结核的诊断价值 | |
| 引用本文： | 张晖,马鑫,刘建建,黄晶晶,冯艳玲,钱雪琴,施霞,陆清,曹佳颖.超声引导下穿刺活检对肺外结核的诊断价值[J].复旦学报(医学版),2021,48(4):503-507. |
| 作者姓名： | 张晖 马鑫 刘建建 黄晶晶 冯艳玲 钱雪琴 施霞 陆清 曹佳颖 |
| 作者单位： | 1 上海市公共卫生临床中心超声科 上海 201508; 2 复旦大学附属中山医院超声科 上海 200032; 3 上海市公共卫生临床中心病理科 上海 201508; 4 上海市公共卫生临床中心检验科 上海 201508 |
| 基金项目： | 上海市科委科研计划项目（18411970800） |
| 摘 要： | 目的 探讨如何提高超声引导下穿刺活检对肺外结核(extrapulmonary tuberculosis,EPTB)的诊断价值.方法 对152例临床疑诊结核或诊断不明病灶的患者进行超声引导下穿刺活检,综合分析组织切片加特殊染色(病理组)、基因X-Pert MTB/RIF检测(基因组)、结核菌培养(菌培组)及涂片这4种方法... |
| 关 键 词： | 结核病 肺外结核(EPTB) 超声 活检 诊断 |
| 收稿时间： | 2020-07-13 |
Value of ultrasound-guided biopsy in the diagnosis of extrapulmonary tuberculosis |
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| ZHANG Hui,MA Xin,LIU Jian-jian,HUANG Jing-jing,FENG Yan-ling,QIAN Xue-qin,SHI Xia,LU Qing,CAO Jia-ying.Value of ultrasound-guided biopsy in the diagnosis of extrapulmonary tuberculosis[J].Fudan University Journal of Medical Sciences,2021,48(4):503-507. | |
| Authors: | ZHANG Hui MA Xin LIU Jian-jian HUANG Jing-jing FENG Yan-ling QIAN Xue-qin SHI Xia LU Qing CAO Jia-ying |
| Institution: | 1 Department of Ultrasound, Shanghui Public Health Clinical Center, Shanghai 201508, China; 2 Department of Ultrasound, Zhongshan Hospital, Fudan University, Shanghai 200032, China; 3 Department of Pathology, Shanghui Public Health Clinical Center, Shanghai 201508, China; 4 Clinical Laboratory, Shanghui Public Health Clinical Center, Shanghai 201508, China |
| Abstract: | Objective To explore how to improve the diagnostic value of ultrasound-guided biopsy for extrapulmonary tuberculosis (EPTB). Methods A total of 152 patients with clinically suspected EPTB or unknown diagnosis underwent ultrasound-guided needle biopsy.The diagnostic efficacy of 4 methods including tissue section with special staining,gene X-Pert MTB/RIF detection,tuberculosis culture and smear was comprehensively analyzed. Results one hundred and eight cases were definitely diagnosed with tuberculosis,and finally 112 cases were diagnosed clinically.The positive rate (detection rate) of diagnosis in each group were as follows:70.4% (88/125) in pathological group with the suspicious diagnosis rate of 5.6% (7/125);71.2% (74/104) in gene X-Pert MTB/RIF group;43.7% (45/103) in culture group;46.4% (52/112) in smear group.There was no false positive case in this study. Conclusion Ultrasonal-guided biopsy is safe,convenient and effective in the diagnosis of EPTB.Combined with relevant laboratory tests,the diagnostic rate can be improved.The diagnostic efficacy of pathology and gene X-Pert MTB/RIF examination is significantly higher than that of culture and smear examinations. |
| Keywords: | tuberculosis extrapulmonary tuberculosis (EPTB) ultrasound biopsy diagnosis |
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