子痫前期复发危险因素分析

The risk factors of recurrent preeclampsia

Objective?The purpose of this study was to investigate the related risk factors of recurrent preeclampsia. Methods?Medical documents of 115 women who had second singleton pregnancy with the previous pregnancy complicated with preeclampsia were retrospectively analyzed from January 2010 to December 2020. These women were divided into two groups, 71 with preeclampsia and 44 without preeclampsia in the subsequent pregnancy. Data was analyzed using univariate analysis and multivariate logistic regression. Results?① Univariate analysis showed that the pre-pregnancy blood pressure, body mass index(BMI), delivered gestational weeks, NICU, birth weight, maternal serum ALB/CR/LDH have an effect on the recurrence of preeclampsia(P<0.05). ② The diagnostic gestational age and pre-existing chronic hypertension of previous pregnancy may have an effect on the recurrence of preeclampsia(P<0.05).③ After adjusting for confounding factors, the recurrence of preeclampsia was found to be influenced by the level of systolic blood pressure before the subsequent pregnancy (OR=1.135, 95%CI 1.067~1.205, P=0.000). Conclusion?The level of systolic blood pressure before the subsequent pregnancy is an independent risk factor for the recurrence of preeclampsia.