| 补阳还五汤预处理对MIRI家兔心肌酶及氧化指标的影响 |
| |
| 引用本文： | 李淑贞,顾宇,张兰兰,杨艳梅,王小宇,刘娜.补阳还五汤预处理对MIRI家兔心肌酶及氧化指标的影响[J].西部医学,2010,22(1):15-17. |
| |
| 作者姓名： | 李淑贞 顾宇 张兰兰 杨艳梅 王小宇 刘娜 |
| |
| 作者单位： | 沧州医学高等专科学校生理教研室,河北,沧州,061001 |
| |
| 摘 要： | 目的观察及探讨补阳五汤对心肌缺血再灌注损伤的保护作用及机制。方法24只家兔随机分为3组：假手术组、模型组、补阳还五汤组。分别预处理1周后，结扎左冠状动脉前降支建立心肌缺血再灌注损伤模型。测定血清中肌酸激酶（CK）、乳酸脱氢酶（LDH）、超氧化物歧化酶（SOD）、丙二醛（MDA）的含量。结果与模型组比较，补阳还五汤组血清CK、LDH及MDA含量明显降低（P〈0．01），血清SOD的活性显著升高（P〈0．01）。结论补阳还五汤可清除氧自由基，减轻心肌缺血再灌注损伤。
|
| 关 键 词： | 补阳还五汤 缺血再灌注 氧化指标 心肌酶 |
Effect of Buyanghuanwu decoction on myocardial enzyme and oxidative indexes of MIRI rabbits |
| |
| LI Shu-zhen,GU Yu,ZHANG Lan-lan,et al.Effect of Buyanghuanwu decoction on myocardial enzyme and oxidative indexes of MIRI rabbits[J].Medical Journal of West China,2010,22(1):15-17. |
| |
| Authors: | LI Shu-zhen GU Yu ZHANG Lan-lan |
| |
| Institution: | LI Shu-zhen,GU Yu,ZHANG Lan-lan,et al(Department of Physiology,Cangzhou Medical School,Cangzhou 061001,Hebei) |
| |
| Abstract: | Objective To explore the protective mechanisms of Buyanghuanwu decoction(BHD) on MIRI.Methods The rabbits were randomly divided into three groups,including sham group,model group and BHD group.After pretreating one week,models of myocardial ischemia reperfusion injury were established by ligating the branch of left coronary artery.CK,LDH,SOD and MDA in serum were detected.Results Compared with model group,CK,LDH,MDA of BHD group were significantly decreased(P<0.01) and the activity of SOD was significantly ... |
| |
| Keywords: | Buyanghuanwu decoction Ischemia reperfusion Oxidative indexes Myocardial Enzyme |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
