| 骨髓增生异常综合征和急性髓系白血病患者骨髓间充质干细胞的生物学特性 |
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| 引用本文： | 柯金勇,林艳娟.骨髓增生异常综合征和急性髓系白血病患者骨髓间充质干细胞的生物学特性[J].福建医科大学学报,2011,45(5):331-334. |
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| 作者姓名： | 柯金勇 林艳娟 |
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| 作者单位： | 福建医科大学附属协和医院血液科,福州,350001 |
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| 基金项目： | 福建省自然科学基金计划项目(2007J0084); 福建省血液病学重点实验室经费(2009J1004) |
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| 摘 要： | 目的 研究骨髓增生异常综合征(MDS)和急性髓系白血病(AML)患者的骨髓间充质干细胞(MSC)的生物学特性.方法 获取7例MDS和21例AML患者的骨髓标本,以6例正常成人的MSC为对照组.体外分离、培养和扩增MSC,显微镜观察MSC的形态和生长特性,免疫细胞化学染色和流式细胞计数进行表型鉴定,RT-PCR法检测MS...
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| 关 键 词： | 骨髓增生异常综合征 白血病 髓样 急性 骨髓 间质干细胞 生物学 |
Biological Characteristics of Mesenchymal Stem Cells Derived From Bone Marrow of Patients with Myelodysplastic Syndrome or with Acute Myeloid Leukemia |
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| KE Jinyong,LIN Yanjuan.Biological Characteristics of Mesenchymal Stem Cells Derived From Bone Marrow of Patients with Myelodysplastic Syndrome or with Acute Myeloid Leukemia[J].Journal of Fujian Medical University,2011,45(5):331-334. |
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| Authors: | KE Jinyong LIN Yanjuan |
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| Institution: | KE Jinyong,LIN Yanjuan Department of Hematology,The Affiliated Union Hospital,Fujian Medical University,Fuzhou 350001,China |
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| Abstract: | Objective To study the biological characteristics of mesenchymal stem cells(MSC) derived from bone marrow of patients with myelodysplastic syndrome(MDS) or with acute myeloid leukemia(AML).Methods MSC were derived from bone marrow samples of 7 patients with MDS,21 patients with AML and 6 normal control subjects,respectively.MSC were cultured and expanded in vitro.The morphology and proliferation of MSC were observed under light microscope;the immuno-phenotype of MSC were determined by immunocytochemistry st... |
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| Keywords: | myelodysplastic syndrome leukemia myeloid acute bone marrow mesenchymal stem cells biology |
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