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适合中药特点的质量评价模式——QAMS研究概述
引用本文:高慧敏,宋宗华,王智民,钱忠直,张启伟. 适合中药特点的质量评价模式——QAMS研究概述[J]. 中国中药杂志, 2012, 37(4): 405-416
作者姓名:高慧敏  宋宗华  王智民  钱忠直  张启伟
作者单位:1. 中国中医科学院中药研究所,北京100700;中药质量控制技术国家工程实验室,北京100700
2. 国家药典委员会,北京,100061
基金项目:国家"重大新药创制"科技重大专项(2009ZX09301-005,2009ZX09308-003);中医药行业科技专项(200707009)
摘    要:在分析总结文献的基础上,概述了适合中药特点的质量评价模式———一测多评法(QAMS)的由来及其在中药质量评价中应用的可行性研究近况,针对该评价模式建立过程中涉及的关键问题进行了深入探讨,展望了QAMS在中药质量控制和评价中的应用前景。

关 键 词:质量评价  一测多评  相对校正因子
收稿时间:2011-06-13

Overview on quantitative analysis of multi-components by single-marker
GAO Huimin,SONG Zonghu,WANG Zhimin,QIAN Zhongzhi and ZHANG Qiwei. Overview on quantitative analysis of multi-components by single-marker[J]. China Journal of Chinese Materia Medica, 2012, 37(4): 405-416
Authors:GAO Huimin  SONG Zonghu  WANG Zhimin  QIAN Zhongzhi  ZHANG Qiwei
Affiliation:Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China; National Engineering Laboratory for Quality Control Technology of Chinese Herbal Medicines, Beijing 100700, China;Chinese Pharmacopoeia Commission, Beijing 100061, China;Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China; National Engineering Laboratory for Quality Control Technology of Chinese Herbal Medicines, Beijing 100700, China;Chinese Pharmacopoeia Commission, Beijing 100061, China;Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China; National Engineering Laboratory for Quality Control Technology of Chinese Herbal Medicines, Beijing 100700, China
Abstract:Based on the previous literatures, the overview on the history and recent advance of the quantitative analysis of multi-components by single-marker (QAMS) was summarized. The key questions of QAMS were also highlighted. It could be considered as a feasible method for the quality control of Traditional Chinese Medicines.
Keywords:quality assesment  quantitative analysis of multi-components by single-marker (QAMS)  relative correction factor (RCF)
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