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Management of central giant cell granuloma of the jaws with intralesional steroid injection and review of the literature
Authors:Doğan Dolanmaz  Alparslan Esen  Ahmet Mihmanlı  Kubilay Işık
Affiliation:1.Faculty of Dentistry, Department of Oral and Maxillofacial Surgery,Sel?uk University,Konya,Turkey;2.Faculty of Dentistry, Department of Oral and Maxillofacial Surgery,Necmettin Erbakan University,Konya,Turkey;3.Faculty of Dentistry, Department of Oral and Maxillofacial Surgery,Bezmialem University,Istanbul,Turkey;4.Faculty of Dentistry, Department of Oral and Maxillofacial Surgery,Necmettin Erbakan University,Konya,Turkey
Abstract:

Purpose

We report the results of the intralesional steroid injections for the management of central giant cell granuloma (CGCG) of the jaws.

Methods

Seven CGCGs were treated with intralesional injection of corticosteroids. To accomplish this, 3.5 mL of triamcinolone and 3.5 mL of 0.5 % marcaine with 1/200,000 epinephrine (total 7 mL) were mixed. An adequate amount of steroid was injected into different areas of the lesion. This procedure was repeated on a weekly basis for 6 weeks.

Results

Clinical and radiological examination showed complete resolution and ossification of the lesions in four patients. Partial recovery was achieved in two patients. One patient did not respond to the treatment and underwent surgical curettage.

Conclusions

We suggest that intralesional steroid injection is safe and effective for the treatment of CGCG, especially in non-aggressive lesions.
Keywords:
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