阴茎异常勃起的病因和危险因素

目的分析阴茎异常勃起的病因和危险因素。方法回顾性分析2009年5月至2013年5月北京大学第一医院男科中心收治的41例阴茎异常勃起患者的病例资料,了解其既往异常勃起发作史、用药史、性生活史、发病诱因和临床实验室检查结果。结果明确病因者15例(15/41,36.59%),其中药物造成11例(11/15,73.33%),包括静脉滴注藻酸双酯钠8例(8/15,53.33%)、抗抑郁药1例(1/15,6.67%)、中成药2例(2/15,13.33%);暴力性生活2例(2/15,13.33%);骑跨伤2例(2/15,13.33%)。并发疾病直肠癌转移患者1例(4%),并发糖尿病2例、高血压病4例、高脂血症6例、抑郁症2例、脑梗塞1例、肝炎1例,反复阴茎异常勃起2例。无明确病因26例(63.41%)。结论骑跨伤造成的阴茎异常勃起均为动脉型,而药物引起的、如藻酸双酯钠,均为静脉型。高血压病、糖尿病和高脂血症导致的血液高黏滞状态可能是阴茎异常勃起的危险因素。

The etiology and risk factors in patients with priapism

Objective To investigate the etiology and risk factors in patients with priapism in the single-center.Methods Clinical data of 41 patients with priapism were enrolled in this study from May 2009 to May 2013.The previous history of priapism,previously used drugs,intercourse,predisposing cause and clinical laboratory test results were analyzed retrospectively.Results Of the 41 patients with priapism,15 had obvious etiology,11 of which （11/15,73.33％） had history of medication which included intravenous polysacharide sulfate in 8 cases （8/15,53.33％）,antidepressant in 1 case （1/15,6.67％）,Chinese herbal medicines in 2 cases （2/15,13.33％）; 2 cases of violent sex （2/15,13.33％）; 2 cases of straddle injury （2/15,13.33 ％）.Of the 41 patients,2 cases were complicated with diabetes mellitus,4 cases with hypertension,6 cases with hyperlipidemia,2 cases with depression,and 1 case with cerebral infarction.2 cases had recurrent priapism.The other 24 cases （24/41,58.5％） were idiopathic priapism.Conclusions Priapism caused by straddle injury is non-ischemic priapism; however,drug-induced priapism,such as alginic sodium diester,is ischemic priapism.Other risk factors included systemic disease,hypertension,diabetes and hyperviscosity caused by hyperlipemia.