| Mechanism of change in cardiac function after mitral valve replacement |
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| 引用本文： | 钱伟,张宝仁,朱家麟,陈如坤,郝家骅,蔡凯华,刘振华. Mechanism of change in cardiac function after mitral valve replacement[J]. 中国人民解放军军医大学学报, 1992, 0(3) |
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| 作者姓名： | 钱伟 张宝仁 朱家麟 陈如坤 郝家骅 蔡凯华 刘振华 |
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| 作者单位： | Departments of Thoracic and Cardiovascular Surgery Changhai Hospital，Second Military Medical University，Shanghai 200433，Departments of Thoracic and Cardiovascular Surgery，Changhai Hospital，Second Military Medical University，Shanghai 200433，Departments of Thoracic and Cardiovascular Surgery，Changhai Hospital，Second Military Medical University，Shanghai 200433，Departments of Thoracic and Cardiovascular Surgery，Changhai Hospital，Second Military Medical University，Shanghai 200433，Departments of Thoracic and Cardiovascular Surgery，Changhai Hospital，Second Military Medical University，Shanghai 200433，Departments of Thoracic and Cardiovascular and Pathology，Changhai Hospital，Second Military Medical University，Shanghai 200433，Department of Pathology，Second Military Medical University，Shanghai 200433 |
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| 基金项目： | Supported by the Youth Foundation of the General Logistics Department of PLA |
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| 摘 要： | Left ventricular contractility was measured using Doppler echocardiography in 37 pa-tients with rheumatic mitral valve disease.Myocardial pathological lesions were studied quanti-tatively by means of the image analysis system and light microscopic examination.The resultsshowed that attenuated cardiac function is due to pathological change of the mitral valve andpathological lesions of the left ventrieular myocardium including increased interstitial fibrosis,thickened intramyocardial arterial wall leading to concentric narrowing of the lumen,hyper-trophic myocardial fiber and endocardial proliferation.Since mitral valve replacement can notcorrect the irreversible myocardial pathological lesions,perioperative protection of the my-ocardium should be emphasized,and intraoperative injury to the myocardium should be mini-mized as far as possible.
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Mechanism of change in cardiac function after mitral valve replacement |
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| Qian Wei,Zhang Baoren,Zhu Jialin,Chen Rukun,Hao Jiahua,Cai Kaihua,Liu Zhenhua Departments of Thoracic and Cardiovascular Surgery and Pathology,Changhai Hospital,Second Military Medical University,Shanghai. Mechanism of change in cardiac function after mitral valve replacement[J]. Journal of Medical Colleges of PLA(China), 1992, 0(3) |
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| Authors: | Qian Wei Zhang Baoren Zhu Jialin Chen Rukun Hao Jiahua Cai Kaihua Liu Zhenhua Departments of Thoracic Cardiovascular Surgery Pathology Changhai Hospital Second Military Medical University Shanghai |
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| Affiliation: | Qian Wei,Zhang Baoren,Zhu Jialin,Chen Rukun,Hao Jiahua,Cai Kaihua,Liu Zhenhua Departments of Thoracic and Cardiovascular Surgery and Pathology,Changhai Hospital,Second Military Medical University,Shanghai 200433 Department of Pathology,Second Military Medical University,Shanghai 200433 |
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| Abstract: | Left ventricular contractility was measured using Doppler echocardiography in 37 pa- tients with rheumatic mitral valve disease.Myocardial pathological lesions were studied quanti- tatively by means of the image analysis system and light microscopic examination.The results showed that attenuated cardiac function is due to pathological change of the mitral valve and pathological lesions of the left ventrieular myocardium including increased interstitial fibrosis, thickened intramyocardial arterial wall leading to concentric narrowing of the lumen,hyper- trophic myocardial fiber and endocardial proliferation.Since mitral valve replacement can not correct the irreversible myocardial pathological lesions,perioperative protection of the my- ocardium should be emphasized,and intraoperative injury to the myocardium should be mini- mized as far as possible. |
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| Keywords: | heart valve prosthesis physiopathology pathology heart function tests myocardial contraction human |
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