| 壳聚糖微球药物释放机制研究进展 |
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| 引用本文： | Li J,Zou Q,Lai X. 壳聚糖微球药物释放机制研究进展[J]. 生物医学工程学杂志, 2011, 28(4): 843-846 |
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| 作者姓名： | Li J Zou Q Lai X |
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| 作者单位： | 成都理工大学材料科学技术研究所;四川大学分析测试中心纳米生物材料研究中心;四川大学化学工程学院; |
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| 基金项目： | 国家自然科学基金青年基金资助项目(51003008) |
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| 摘 要： | 近年来已有多种药物实现了以壳聚糖微球作为缓控释载体,并在生物医学领域展现出良好的应用前景,成为缓控释剂型研究的热点之一。目前对壳聚糖微球释放机制的研究进展落后于壳聚糖载药微球制备与应用的研究进展,而加强壳聚糖载药微球药物释放机制的研究,有利于更好地了解药物的释放行为和释放影响因素,并对深入研究壳聚糖缓释载药体系的制备与应用具有重要意义。主要从壳聚糖微球的药物释放机制、药物释放行为描述、药物释放影响因素等方面进行了综述。
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| 关 键 词： | 壳聚糖 微球 缓释 药物释放 机制 |
Review on progress of research on drug releasing mechanism of chitosan microspheres |
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| Li Junfeng,Zou Qin,Lai Xuefei. Review on progress of research on drug releasing mechanism of chitosan microspheres[J]. Journal of biomedical engineering, 2011, 28(4): 843-846 |
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| Authors: | Li Junfeng Zou Qin Lai Xuefei |
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| Affiliation: | Li Junfeng1 Zou Qin2 Lai Xuefei3 1(Institute of Material Science and Technology,Chengdu University of Technology,Chengdu 610059,China)2(Research Center for Nano Biomaterials,Analytical & Testing Center,Sichuan University,Chengdu 610064,China)3(College of Chemical Engineering,Chengdu 610065,China) |
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| Abstract: | Variety of drugs-loaded chitosan microspheres have been used as sustained release carrier in recent years,which has shown a good prospect in biomedical field.Therefore,chitosan microspheres have been one of the research hotspots in controlled release drug delivery system.Nowadays the research in releasing mechanism of drug-loaded chitosan microspheres lags obviously behind the research in preparation and application.Moreover further research in drug releasing mechanism of chitosan microspheres is beneficial... |
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| Keywords: | Chitosan Microspheres Sustained release Drug releasing Mechanism |
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