| 炎性介质SAA和CRP术前评估卵巢癌的临床价值 |
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| 引用本文： | 魏江霞,唐乾坤,杨晋容,张玲,李军,王梅. 炎性介质SAA和CRP术前评估卵巢癌的临床价值[J]. 西部医学, 2011, 23(9): 1676-1678,1680. DOI: 10.3969/j.issn.1672-3511.2011.09.020 |
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| 作者姓名： | 魏江霞 唐乾坤 杨晋容 张玲 李军 王梅 |
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| 作者单位： | 广元市第一人民医院妇科,四川广元,628017 |
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| 摘 要： | 目的探讨卵巢癌患者炎性介质CRP、SAA与肿瘤标记物CA125的相关性及其对卵巢肿瘤术前分期的价值。方法纳入150例卵巢癌患者于术前3天测定血清CA125、CRP和SAA的水平,分析炎性介质和肿瘤标记物的关系并与FIGO分期比较。结果术前SAA、CRP与CA125三者之间均有相关性（P〈0.05）。在不同的FIGO分期之间差异有统计学意义,其中CRP和SAA与FIGO分期呈正相关。建立诊断进展期卵巢癌的ROC曲线,SAA的ROC曲线下面积AZ=0.993（P〈0.001）,CRP的AZ=0.922（P〈0.05）,CA125的AZ=0.871（P〈0.05）。结论炎性介质和肿瘤标记物具有一定的相关性,应用SAA和CRP诊断进展期卵巢癌具有重要的临床价值。
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| 关 键 词： | 卵巢肿瘤 C-反应蛋白 血清淀粉样蛋白A CA125 肿瘤分期 |
Clinical value of inflammatory factors CRP and SAA in preoperative evaluation for ovarian cancer |
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| WEI Jiang-Xia,TANG Qian-kun,YANG Jin-rong,et al. Clinical value of inflammatory factors CRP and SAA in preoperative evaluation for ovarian cancer[J]. , 2011, 23(9): 1676-1678,1680. DOI: 10.3969/j.issn.1672-3511.2011.09.020 |
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| Authors: | WEI Jiang-Xia TANG Qian-kun YANG Jin-rong et al |
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| Affiliation: | WEI Jiang-Xia,TANG Qian-kun,YANG Jin-rong,et al (Department of Gynecology,The First People's Hospital of Guangyuan,Guangyuan 628017,Scihuan) |
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| Abstract: | Objective To investigate the correlation between inflammatory factors and tumor markers,and evaluate the application of them in the preoperative staging of ovarian cancer.Methods Levels of CRP,SAA,and CA125 were obtained from 150 ovarian cancer patients preoperatively in order to analyze the relationship within these biomarkers and with the FIGO stage.Results SAA showed correlation with CRP and CA125(P<0.05).Serum levels of CRP(P<0.05),SAA(P<0.05) and CA125(P<0.05)had statistically significant differences b... |
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| Keywords: | Ovarian cancer C-reactive protein Serum amyloid A protein Cancer antigen 125 Neoplasm staging |
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