超声实时组织弹性成像在甲状腺弥漫性疾病中的初步应用

目的 探讨超声实时组织弹性成像对甲状腺弥漫性疾病的诊断价值.方法 采用主成分分析对123例甲状腺弥漫性疾病患者和42例甲状腺正常者的11个弹性定量参数进行综合分析,把综合评价函数值命名为硬度指数(stiffness index,SI)来反映甲状腺疾病组织的弹性信息,并用方差分析比较SI在各组间的差异.结果 慢性淋巴细胞性甲状腺炎SI为 86.37±20.45,亚急性甲状腺炎SI为 86.14±19.95,原发性甲状腺功能亢进SI为 54.68±21.69,正常对照组SI为 41.34±15.59.慢性淋巴细胞性甲状腺炎、亚急性甲状腺炎、原发性甲亢与正常对照组之间SI差异有统计学意义(P<0.05);原发性甲亢与慢性淋巴细胞性甲状腺炎、亚急性甲状腺炎之间的SI差异有统计学意义(P<0.05);慢性淋巴细胞性甲状腺炎与亚急性甲状腺炎之间SI差异无统计学意义(P>0.05).结论 实时超声弹性成像可间接反映甲状腺病变组织的硬度,对甲状腺弥漫性疾病具有一定的诊断价值.

Abstract：

Objective To explore the diagnosis value of ultrasound real-time elastography in thyroid diffuse diseases.Methods Eleven elastic quantitative parameters of 123 patients with thyroid diffuse diseases and 42 healthy volunteers obtained from the ultrasound real-time elastography were analyzed with principal components analysis to attain a comprehensive evaluation value which was named stiffness index(SI),reflecting the organization elastic information of different thyroid diffuse diseases.SI among each group was compared by ANOVA.Results Chronic lymphocytic thyroiditis SI was 86.37±20.45,subacute thyroiditis SI was 86.14±19.95,primary hyperthyroidism SI was 54.68±21.69,normal control group SI was 41.34±15.59,respectively.The SI between chronic lymphocytic thyroiditis,subacute thyroiditis,primary hyperthyroidism and normal controls had significant statistical differences (P<0.05),the SI between primary hyperthyroidism and chronic lymphocytic thyroiditis,subacute thyroiditis had significant statistical differences (P<0.05),the SI between chronic lymphocytic thyroiditis and subacute thyroiditis had no significant statistical difference (P>0.05).Conclusions Ultrasound real-time elastography could indirectly reflect the stiffness information of thyroid lension tissue and have a certain degree of diagnosis value in thyroid diffuse disease.

Preliminary application of ultrasound real-time elastography in diagnosis of thyroid diffuse disease

Objective To explore the diagnosis value of ultrasound real-time elastography in thyroid diffuse diseases.Methods Eleven elastic quantitative parameters of 123 patients with thyroid diffuse diseases and 42 healthy volunteers obtained from the ultrasound real-time elastography were analyzed with principal components analysis to attain a comprehensive evaluation value which was named stiffness index(SI),reflecting the organization elastic information of different thyroid diffuse diseases.SI among each group was compared by ANOVA.Results Chronic lymphocytic thyroiditis SI was 86.37±20.45,subacute thyroiditis SI was 86.14±19.95,primary hyperthyroidism SI was 54.68±21.69,normal control group SI was 41.34±15.59,respectively.The SI between chronic lymphocytic thyroiditis,subacute thyroiditis,primary hyperthyroidism and normal controls had significant statistical differences (P<0.05),the SI between primary hyperthyroidism and chronic lymphocytic thyroiditis,subacute thyroiditis had significant statistical differences (P<0.05),the SI between chronic lymphocytic thyroiditis and subacute thyroiditis had no significant statistical difference (P>0.05).Conclusions Ultrasound real-time elastography could indirectly reflect the stiffness information of thyroid lension tissue and have a certain degree of diagnosis value in thyroid diffuse disease.