| 慢乙肝阿德福韦酯治疗过程外周血T淋巴细胞亚群变化 |
| |
| 引用本文： | 郭炜,张倩华. 慢乙肝阿德福韦酯治疗过程外周血T淋巴细胞亚群变化[J]. 现代预防医学, 2011, 38(7): 1342-1343 |
| |
| 作者姓名： | 郭炜 张倩华 |
| |
| 作者单位： | 广东省中山市第二人民医院,中山,528400 |
| |
| 摘 要： | [目的]研究阿德福韦酯抗病毒治疗过程中慢乙肝患者外周血T淋巴细胞亚群的变化情况。[方法]选取151例使用阿德福韦酯治疗的慢乙肝患者,分为HBeAg阳性组,及HBeAg阴性组,分析其治疗过程中CD4+/CD8+水平变化情况。[结果]HBeAg阳性组患者治疗48周出现血清学应答者CD4+/CD8+比值较无出现血清学应答者高;HBeAg阴性者出现病毒学应答者CD4+/CD8+比值较无出现应答者高;两组出现应答患者48周后CD4+/CD8+比值无显著差异。[结论]使用阿德福韦酯抗病毒患者中,出现应答者的细胞免疫功能有所恢复。
|
| 关 键 词： | 慢性乙型肝炎 阿德福韦酯 T淋巴细胞亚群 |
CHANGES OF PERIPHERAL BLOOD T LYMPHOCYTE SUBSETS DURING ADEFOVIR DIPIVOXIL THERAPY FOR CHRONIC HEPATITIS B |
| |
| GUO Wei,ZHANG Qian-hua. CHANGES OF PERIPHERAL BLOOD T LYMPHOCYTE SUBSETS DURING ADEFOVIR DIPIVOXIL THERAPY FOR CHRONIC HEPATITIS B[J]. Modern Preventive Medicine, 2011, 38(7): 1342-1343 |
| |
| Authors: | GUO Wei ZHANG Qian-hua |
| |
| Affiliation: | GUO Wei,ZHANG Qian-hua.(Zhongshan City Second People's Hospital in Guangdong Province,Zhongshan 528400,China) |
| |
| Abstract: | [Objective]To study the changes of T lymphocyte subsets in peripheral blood when antiviral adefovir dipivoxil treatment used in chronic hepatitis B patients.[Methods]151 patients with chronic hepatitis B treated by adefovir dipivoxil were divided into HBeAg-positive group and HBeAg-negative group,then analyzed the changes of CD4 +/CD8 + level in treatment.[Results]The CD4 +/CD8 + ratio of HBeAg-positive patients with 48 weeks treatment who appeared serological responses was higher than those without serolog... |
| |
| Keywords: | Chronic hepatitis B Adefovir dipivoxil T lymphocyte subsets |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
