Pharmacokinetics and Pharmacodynamics of Broccoli Sprouts on the Suppression of Prostate Cancer in Transgenic Adenocarcinoma of Mouse Prostate (TRAMP) Mice: Implication of Induction of Nrf2, HO-1 and Apoptosis and the Suppression of Akt-dependent Kinase Pathway期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Pharmacokinetics and Pharmacodynamics of Broccoli Sprouts on the Suppression of Prostate Cancer in Transgenic Adenocarcinoma of Mouse Prostate (TRAMP) Mice: Implication of Induction of Nrf2, HO-1 and Apoptosis and the Suppression of Akt-dependent Kinase Pathway

Authors:	Young-Sam Keum Tin Oo Khor Wen Lin Guoxiang Shen Ki Han Kwon Avantika Barve Wenge Li Ah-Ng Kong

Affiliation:	(1) Department of Pharmaceutics and Ernest Mario School of Pharmacy, Rutgers The State University of New Jersey, 160 Frelinghuysen Road, Piscataway, New Jersey 08854, USA;(2) Present address: Novartis Institutes for BioMedical Research, DMPK-Translational Sciences (TS), East Hanover, New Jersey 07936, USA;(3) Present address: Metabolism and Pharmacokinetics, Research & Development Bristol- Myers Squibb Co, Princeton, New Jersey 08543, USA;(4) Present address: Bioanalytical R & D, Wyeth Pharmaceuticals, 401 N Middletown Rd, Pearl River, New York 10965, USA;

Abstract:	Purpose In the present study, we have evaluated the pharmacokinetics and the in vivo prostate chemopreventive activity of broccoli sprouts.

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