孕11～14周胎儿三尖瓣频谱测量与分析

目的 探讨胎儿早孕期检测三尖瓣频谱的临床价值和方法.方法 对孕11～14周胎儿进行超声检查,测量头臀长、颈部透明层、三尖瓣频谱等,并观察胎儿头颅、躯干、四肢等结构以发现严重胎儿畸形.对所有胎儿进行孕期超声检查、唐氏综合征筛查,可疑者进一步行染色体检查,并随访至出生后6个月.结果 共检查早孕期胎儿262例,其中249例成功获得三尖瓣频谱,检查成功率95%.发现三尖瓣反流胎儿9例,其中2例为21-三体,3例为严重心脏结构异常,1例合并脐疝,2例胎死宫内,1例染色体正常者随访至生后8个月未发现异常.结论 早孕期胎儿三尖瓣频谱测量简易可行,三尖瓣反流是胎儿染色体异常、严重心脏结构异常及不良预后的有效预测指标.

Abstract：

Objective To investigate the clinical value and method of fetal tricuspid regurgitation in the first trimester.Methods Fetuses were performed ultrasonography at 11 to 14 gestational weeks,measuring crown rump length,nuchal translucency and acquiring tricuspid waveform.All the fetuses were followed up until 6 months after birth,including prenatal ultrasound examination,maternal serum biochemistry and karyotype test.Results A total of 262 fetuses were performed ultrasonography in the first trimester,the tricuspid waveform were acquired successfully in 249 (95%).Nine cases with tricuspid regurgitation were detected,including 3 cases of trisomy 21,3 cases with complex heart defects,one case with omphalocele,two resulted in intrauterine death and one case of normal chromosome and phenotype.Conclusions Tricuspid waveform is relatively easier to examine and assessment.Tricuspid regurgitation is a useful first-trimester ultrasound marker for the detection of chromosomal abnormalities,cardiac defects,and adverse pregnancy outcome.

Measurement and assessment of fetal tricuspid waveform in first-trimester

Objective To investigate the clinical value and method of fetal tricuspid regurgitation in the first trimester.Methods Fetuses were performed ultrasonography at 11 to 14 gestational weeks,measuring crown rump length,nuchal translucency and acquiring tricuspid waveform.All the fetuses were followed up until 6 months after birth,including prenatal ultrasound examination,maternal serum biochemistry and karyotype test.Results A total of 262 fetuses were performed ultrasonography in the first trimester,the tricuspid waveform were acquired successfully in 249 (95%).Nine cases with tricuspid regurgitation were detected,including 3 cases of trisomy 21,3 cases with complex heart defects,one case with omphalocele,two resulted in intrauterine death and one case of normal chromosome and phenotype.Conclusions Tricuspid waveform is relatively easier to examine and assessment.Tricuspid regurgitation is a useful first-trimester ultrasound marker for the detection of chromosomal abnormalities,cardiac defects,and adverse pregnancy outcome.