Maltose-binding protein isolated from <Emphasis Type="Italic">Escherichia coli</Emphasis> induces Toll-like receptor 2-mediated viability in U937 cells |
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| Authors: | Zhao Xiaoxia Ni Weihua Zhang Qingyong Wang Fengli Li Yingying Sun Xiaxia Liu Zhonghui Tai Guixiang |
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| Institution: | (1) Pulmonary Center, Boston University School of Medicine, 02118-2394 Boston, MA, USA; |
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| Abstract: | Background Stimulation of Toll-like receptors (TLRs) by microbial products has been utilised to potentiate immune responses against haematologic
malignancies. The maltose-binding protein (MBP) of Escherichia coli could induce the activation of immune cells via TLR4. The aim of the present study was to investigate whether TLRs mediated
the biological effects of MBP on U937 and Jurkat cells in vitro. |
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