卵巢原发恶性淋巴瘤的诊断与鉴别诊断

目的:研究卵巢原发恶性淋巴瘤的诊断、鉴别诊断及临床特点.方法:用免疫组织化学及组织病理学方法观察39例卵巢恶性肿瘤,包括初次病理诊断的2例恶性淋巴瘤和37例具有小圆形细胞为主要特征的卵巢恶性肿瘤.结果:发现5例组织病理学特点、免疫组织化学标记符合卵巢原发恶性淋巴瘤,所有病例临床均诊断为畸胎瘤或腹部包块,临床特点以腹痛,腹部包块为主或无症状.结论:卵巢原发恶性淋巴瘤罕见、起病隐袭、症状不典型,临床及病理诊断很困难,单凭组织化学方法很难与其它小圆形细胞肿瘤鉴别,免疫组织化学标记有重要价值.

The diagnosis and differential diagnosis of ovarian primary lymphoma

Objective: To investigate diagnosis and differential diagnosis of ovarian primary lymphoma. Methods: Immunohis-tochemical and histopathological method were applied to study 39 cases ovarian primary malignant tumor including 2 cases lymphoma as first pathological diagnosis and 37 cases malignant tumor with the character of small round cell neoplasmas. Investigate the clinical character including.clinical diagnosis and histories. Results: 5 cases, its immunohistchemistry markers, histopathological character and disease histories were accord with ovarian primary lymphoma. their first clinical diagnosis were teratoma or abdominal mass, main clini-cal character were abdominal pain and mass, or no signs. Conclusion: Ovarian primary lymphoma is rare, chronic and usually no special signs. Clinical and pathological diagnosis may be very difficult. it' s almost not different from other small round ?cell neoplasmas clearly by only histopathological method, Immunohistochemistry markers is very useful.