Staged sentinel lymph node biopsy before mastectomy facilitates surgical planning for breast cancer patients |
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Authors: | Klauber-Demore Nancy Calvo Benjamin F Hultman C Scott Kim Hong Jin Meyers Michael O Damitz Lynn Frank Jill S Stitzenberg Karen B Sartor Carolyn I Ollila David W |
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Institution: | Division of Surgical Oncology, University of North Carolina at Chapel Hill, 3010 Old Clinic Bldg., CB No. 7213, Chapel Hill, NC 27599, USA. nancy_demore@med.unc.edu |
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Abstract: | BACKGROUND: In patients with breast cancer who choose mastectomy with immediate reconstruction, the sentinel lymph node (SLN) status on permanent histology may complicate treatment if a metastasis is found. The purpose of this study was to determine how performing an SLN biopsy (SLNB) before the definitive operation would influence subsequent surgical procedures. METHODS: Our SLN database was searched for patients who underwent staged SLNB with subsequent mastectomy between 2001 and 2004. RESULTS: Twenty-five patients with 27 breast cancers underwent SLNB before mastectomy. Of them, 9 of 27 (33%) were node positive. All 9 patients underwent modified radical mastectomy. Three node-positive patients did not undergo immediate reconstruction. Of the remaining 6 node-positive patients, 5 underwent reconstruction with autologous tissue rather than a tissue expander. In contrast, 6 of 16 (37%) node-negative patients underwent reconstruction with a tissue expander. CONCLUSIONS: Staged SLNB assists in selecting the appropriate operation in patients who are considering immediate reconstruction. |
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Keywords: | Axillary lymph node dissection Axillary staging Postmastectomy radiation Reconstruction Transverse rectus abdominis musculocutaneous delay |
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