19530例泌尿生殖道感染患者支原体感染及药敏结果分析 |
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引用本文: | 龚娅,段德令,何宗忠,王晓冬,史秋霞,林林东,欧炜华. 19530例泌尿生殖道感染患者支原体感染及药敏结果分析[J]. 重庆医学, 2015, 0(25): 3539-3541. DOI: 10.3969/j.issn.1671-8348.2015.25.028 |
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作者姓名: | 龚娅 段德令 何宗忠 王晓冬 史秋霞 林林东 欧炜华 |
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作者单位: | 广州军区广州总医院 157 分院检验科,广州,510510 |
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摘 要: | 目的:分析该地区泌尿生殖道支原体感染及耐药状况,为临床合理用药提供依据。方法采用支原体培养、鉴定、药敏试剂盒对19530例泌尿生殖道感染患者的送检标本进行检测,分析支原体感染及药敏情况。结果19530例送检样本中,支原体阳性11178例,阳性率为57.24%,其中解脲支原体(Uu)、人型支原体(Mh)、Uu+Mh 混合感染阳性率分别为44.63%、0.44%和12.17%;女性支原体阳性率高于男性,差异有统计学意义(P <0.05);2008~2014年支原体阳性率呈上升趋势;支原体对交沙霉素、强力霉素、米诺环素、克拉霉素敏感率分别为88.57%、84.32%、76.09%、71.53%,对喹诺酮类抗菌药物耐药率高;Uu、Mh 和 Uu+Mh 3类感染对12种抗菌药物的耐药种数递增。结论泌尿生殖道感染以 Uu 感染为主,Mh 感染多以混合感染方式出现;交沙霉素、强力霉素是该地区治疗支原体的首选药物,临床可参考药敏结果合理用药。支原体多重耐药情况严重,应引起临床重视。
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关 键 词: | 支原体 泌尿生殖道 药敏试验 耐药率 多重耐药 |
Analysis on the infection and drug susceptibility of mycoplasma in 1 9 530 cases of urogenital tract infections |
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Abstract: | Objective To analyze the status of mycoplasma infection and drug resistance in the local area,and provide the ba-sis for clinical rational drug use.Methods The specimens obtained from 1 9 530 patients with urogenital tract infection were detec-ted by adopting mycoplasma culture,identification and drug sensitivity integration kit.Mycoplasma infection and drug susceptibility were analyzed.Results In the total of 1 9 530 suspected patients specimens,1 1 1 78 cases were positive with a positive rate 57.24%.The positive rate of ureaplasma urealyticum (Uu)and mycoplasma hominis (MH)was 44.63% and 0.44% respectively and the positive rate of Uu and Mh mixed infection was 12.1 7%.The positive rate of female was higher than that of male and the difference was statistically significant(P <0.05).The positive rate of mycoplasma in 2008-2014 was on the rise;The sensitive rate of mycoplasma to josamycin,doxycycline,minocycline element,clarithromycin was 88.57%,84.32%,76.09% and 71.53% respec-tively,mycoplasma was highly drug resistance to quinolone antibiotics;mixed infection resistance was higher than that of single in-fection;The number of drug resistance of Uu,MH and Uu+MH to 12 kinds of antibiotics increase.Conclusion Mycoplasma infec-tion in urogenital tract is mainly caused by Uu and Mh infection is in mixed infection way;josamycin,doxycycline is the first choice for treatment of mycoplasma in this region.Rational drug choise can be based on the drug susceptibility test.Multiple drug resist-ance of mycoplasma is serious and should be paid attention to. |
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Keywords: | mycoplasma urogenital tract drug susceptibility test drug resistance rate multiple drug resistance |
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