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Evidence for preserved insulin responsiveness in the aging rat brain
Authors:Engel  Matthew G.  Smith  Jeremy  Mao  Kai  Quipildor  Gabriela Farias  Cui   Min-Hui  Gulinello   Maria  Branch   Craig A.  Gandy  Samuel E.  Huffman  Derek M.
Affiliation:1.Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY, 10461, USA
;2.Institute for Aging Research, Albert Einstein College of Medicine, 1300 Morris Park Ave, Golding Building Room 201, BronxBronx, NY, 10461, USA
;3.Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, GA, USA
;4.Department of Medicine, Albert Einstein College of Medicine, Bronx, NY, 10461, USA
;5.Department of Radiology, Albert Einstein College of Medicine, Bronx, NY, 10461, USA
;6.Dominick S. Purpura Department of Neuroscience, Behavioral Core Facility, Albert Einstein College of Medicine, Bronx, NY, USA
;7.Department of Neurology and the Mount Sinai Center for Cognitive Health, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA
;8.Department of Psychiatry and the Mount Sinai Alzheimer’s Disease Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA
;
Abstract:GeroScience - Insulin appears to exert salutary effects in the central nervous system (CNS). Thus, brain insulin resistance has been proposed to play a role in brain aging and dementia but is...
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