Spurious Elevation of Glucose Concentration during Administration of High Dose of Ascorbic Acid in a Patient with Type 2 Diabetes on Hemodialysis |
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| Authors: | Soo Kyoung Kim Jong Ryeal Hahm Ho-Su Kim Sungsu Kim Tae Sik Jung Jung Hwa Jung Hye Ryun Lee Deok Ryong Kim |
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| Affiliation: | 1.Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju, Korea.;2.Institute of Health Sciences, Gyeongsang National University School of Medicine, Jinju, Korea.;3.Department of Laboratory Medicine, Gyeongsang National University School of Medicine, Jinju, Korea.;4.Department of Biochemistry, Gyeongsang National University School of Medicine, Jinju, Korea. |
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| Abstract: | We describe herein a case of life-threatening hypoglycemia due to spurious elevationof glucose concentration during the administration of ascorbic acid in a type 2 diabetic patient. A 31-year-old female was admitted for proliferative diabetic retinopathytreatment and prescribed high dose ascorbic acid. During hospitalization, she suddenly lost her consciousness and her glucose concentration was 291 mg/dL, measured using self-monitoring blood glucose (SMBG) device, while venous blood glucose concentration was 12 mg/dL. After intravenous injection of 50% glucose solution, the patient became alert. We reasoned that glucose measurement by SMBG device was interfered by ascorbic acid. Physicians should be aware of this interference; high dose ascorbic acid may cause spurious elevation of glucose concentration when measuring with SMBG devices. |
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| Keywords: | Self-monitoring of blood glucose ascorbic acid hypoglycemia |
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