| Abstract: | Histoplasmosis is a systemic mycosis endemic in extensive areas of the Americas. Theauthors report on an urban adult male patient with uncommon oral-cutaneous lesionsproven to be histoplasmosis. Additional investigation revealed unnoticed HIVinfection with CD4+ cell count of 7/mm3. The treatment was performed withamphotericin B, a 2065 mg total dose followed by itraconazole 200mg/daily plusantiretroviral therapy with apparent cure. Histoplasmosis is an AIDS-definingopportunistic disease process; therefore, its clinical diagnosis must drive fulllaboratory investigation looking for unnoted HIV-infection. |
