Abstract: | Histoplasmosis is a systemic mycosis endemic in extensive areas of the Americas. The
authors report on an urban adult male patient with uncommon oral-cutaneous lesions
proven to be histoplasmosis. Additional investigation revealed unnoticed HIV
infection with CD4+ cell count of 7/mm3. The treatment was performed with
amphotericin B, a 2065 mg total dose followed by itraconazole 200mg/daily plus
antiretroviral therapy with apparent cure. Histoplasmosis is an AIDS-defining
opportunistic disease process; therefore, its clinical diagnosis must drive full
laboratory investigation looking for unnoted HIV-infection. |