A variant on the kappa opioid receptor gene (OPRK1) is associated with stress response and related drug craving,limbic brain activation and cocaine relapse risk |
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Authors: | K Xu D Seo C Hodgkinson Y Hu D Goldman R Sinha |
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Affiliation: | 1.Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA;2.Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, USA;3.Center for Biomedical Informatics and Information Tech, National Cancer Institute, Bethesda, MD, USA;4.Child Study Center, Yale School of Medicine, New Haven, CT, USA;5.Stress Center, Yale University, New Haven, CT, USA |
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Abstract: | |
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Keywords: | cocaine craving, limbic– midbrain hyperactivation, OPRK1, relapse, stress |
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