铜绿假单胞菌耐药分析

【目的】分析本院铜绿假单胞菌的耐药情况，为医院合理使用抗菌药提供可靠的实验依据。【方法】收集本院2001年3月-2004年2月间各种临床标本分离的铜绿假单胞菌214株，应用API细菌鉴定系统进行鉴定，并用K-B法进行药敏实验。【结果】铜绿假单胞菌对亚胺培南、哌啦西林／三唑巴坦、哌啦西林、头孢唑林、头孢呋辛、头孢他啶、头孢哌酮、头孢吡肟、庆大霉素、阿米卡星、环丙沙星的耐药率分别为1．0％、18．5％、20．3％、92．1％、90．6％、12．7％、15．1％、8．2％、32．3％、9．4％、8．9％。【结论】临床应根据药敏实验合理使用抗生素，以减少耐药菌株的产生。

Analysis on the antibiotic resitance of P.aeruginosa

To investigate the antibiotic resistance of P.aeruginosa in our hospital and provid the credible antimicrobial susceptibility test results for clinical antibiotic.A total clinical isolates of P.aeruginosa were collected from different districts of our hospital from January 2001 to Febuary 2004.Bactera were identified with API system.K-B methods were performed to detect the drug resistance of theses strains.Antibiotic resistant rates was imipenem 1 0%,piperacillin-tazobactam 18 5%,piperacillin 20 3%,cefazolin 92 1%,cefuroxime 90 6%,ceftazidime 12 7%,cefoperazone 15 1%,cefepime 8 2%,gentamicin 32 3%,amikacin 9 4%,ciprofloxacin 8 9%.[Conclusion]Clinical use antibiotic shold accord to the antimicrlbial susceptibility test results.This can reduce or prevent the occurrence of drug resistance.