冠状动脉造影术535例的安全性及综合文献资料分析

用Judkins法行选择性冠状动脉造影术（CAG），记录术中、术后出现的各种并发症。主要并发症定义为死亡、急性心肌梗死、急性心力衰竭、严重心律失常及血管并发症等。检索国内1999年以前有关CAG并发症方面的主要文献，综合分析其并发症发生率。535例患者心室颤动发生率0．37％（2／535），严重缓慢性心律失常发生率1．31％（7／535），血管并发症发生率1．31％（7／535），无死亡、急性心肌梗死、急性心力衰竭及动脉栓塞、夹层等严重并发症。主要并发症发生率2．99％（16／535），与文献资料3．01％（141／4679）比较差异无显著性。说明冠状动脉造影术有出现严重并发症可能，但通过有效防治其安全性临床是可以接受的。

ANALYSIS OF SAFETY OF CORONERY ARTERY ANGIOGRAPHY IN 535 PATIENTS AND REVIEW OF LITERATURE

All the complications from 535 patients undergoing selective coronary artery angiogram by using Judkins method have been documented during and after the procedures and compared with collected data from Chinese papers published before 1999.The main complications included death, acute myocardial infarction,acute heart failure, severe arrhythmia,and peripheral vessel complication.In 535 patients the main complication rate was 2 99%(16 of 535),in which ventricular fibrillation rate accounted for 0 37%(2 of 535),severe bradycardia for 1 31%(7 of 535),and peripheral vessel complications for 1 31%(7 of 535).There was no death,no AMI, no heart failure,no artery embolus,no aortic dissection.Compared with 3 01% (141 of 4679) of complications for collected data from domestic literature,there was no significant difference.The data suggested that with effective preventive measures,coronary artery angiogram is a reasonably safe proceduce,although there is still a possibility to have server complications.