| 重度子痫前期及子痫发生可复性后部脑白质综合征的MRI特点及临床分析 |
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| 引用本文： | 王玉萍,陈亚琼,孙志华,牛秀敏. 重度子痫前期及子痫发生可复性后部脑白质综合征的MRI特点及临床分析[J]. 实用妇产科杂志, 2009, 25(1) |
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| 作者姓名： | 王玉萍 陈亚琼 孙志华 牛秀敏 |
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| 作者单位： | 1. 武警医学院附属医院,天津,300162
2. 天津医科大学总医院,天津,300052 |
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| 摘 要： | 目的:探讨重度子痫前期及子痫发生可复性后部脑白质综合征(posterior reversible en-cephalopathy syndrome,PRES)的磁共振成像(MRI)特点和临床特点.方法:对26例重度子痫前期患者和14例子痫患者进行脑部MRI检查,根据MRI检查结果将患者分为PRES组和对照组.并对病变的部位及病变的信号特点、临床症状、血压及实验室检查特点进行分析.结果:①MRI检查40例患者,其中MRI显示正常的患者12例(对照组),MRI显示PRES患者26例(PRES组),脑梗死患者1例、颅内静脉窦血栓患者1例;②PRES组MRI表现为皮层和皮层下病变.呈现T1W信号增强和T2信号减弱.病变部位表现为:枕叶均受累及,其次为项叶、额叶和颞叶,少数累及基底节和脑桥;③PRES组与对照组相比,临床症状中抽搐发生率前者高于后者;同时前者血浆尿酸水平也高于后者.结论:可复性后部脑病综合征是重度子痫前期及子痫发生脑病的主要特征性损害,推测与内皮细胞损伤有关的血脑屏障受损可能在发病中起重要作用.
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| 关 键 词： | 妊娠 重度子痫前期 子痫 磁共振成像 可复性后部脑病综合征 |
Clinical and MRI Appearance of Preeclampsia-eclampsia with Posterior Reversible Encephalopathy Syndrome |
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| WANG Yuping,CHEN Yaqiong,SUN Zhihua,et al. Clinical and MRI Appearance of Preeclampsia-eclampsia with Posterior Reversible Encephalopathy Syndrome[J]. Journal of Practical Obstetrics and Gynecology, 2009, 25(1) |
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| Authors: | WANG Yuping CHEN Yaqiong SUN Zhihua et al |
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| Affiliation: | General Hospital of Tianjin Medical University;Tianjin 300052;China |
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| Abstract: | Objective:To investigate the clinical parameters and appearance of magnetic resonance image(MRI) associated with the posterior reversible encephalopathy syndrome(PRES) in patients with preeclampsia-eclampsia.Methods: 26 preeclampsia and 14 eclampsia patients were examined using MRI.Patients were divided into two groups,the normal group,in which patients had normal image and the PRES group.The distribution and signal patterns of the lesions,clinical features and laboratory data were compared between the two ... |
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| Keywords: | Pregnancy Pre-eclampsia Eclampsia Magnetic resonance image Posterior reversible encephalopathy syndrome |
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