比索咯尔与硝苯吡啶降压效应的对比观察

将62例高血压病患者随机分为A、B两组进行比索咯尔与硝本比啶降压疗效的对比观察．结果表明，两药对轻中度高血压的疗效相近，但对重度高血压硝苯比啶的效果优于吡索咯尔（P＜0．001），而降低心率（HR）及心肌耗氧量（MOC）的作用，后者优于前者（P＜0．001）。提示比索咯尔适用于HR及MOC增加的轻中度高血压病者。

A COMPARISON OF EFFECTS BETWEEN BISOPROLOL AND NIFEDIPINE ON HYPERTENSION

62 cases with essential hypertension were randomly assigned to either Bisoprolol (group A) or nifedipine (group B) treatment for 3 weeks. Significant therapeutic effect was observed in both groups. The effect of Nifedipine was superior to that of Bisoprolol in severe hypertension. On the contrary. the heart rate and myocardial oxygen consumption was significantly reduced in group A. It indicated that Bisoprolol was suitable fOr mild or moderate hypertension with high heart rate.