|
|||||
|
|
Topiramate induces type 3 renal tubular acidosis by inhibiting renal carbonic anhydrase. |
|
| Authors: | Anne Sacré Fran?ois Jouret Daniel Manicourt Olivier Devuyst |
| Institution: | 1Division of Nephrology 2Division of Rheumatology St-Luc Academic Hospital Université catholique de Louvain Medical School, Brussels Belgium |
| Abstract: | Sir, We report a case of mixed (type 3) renal tubular acidosis (RTA)associated with the anti-convulsant drug topiramate used formigraine prophylaxis. A 47-year-old woman treated with topiramate(150 mg/day) since 12 months for invalidating migraine was referredfor a metabolic acidosis evidenced in a routine blood sampling.She complained of muscle weakness |
| Keywords: | |
| 本文献已被 Oxford 等数据库收录！ | |