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Diagnose, Prophylaxe und Therapie der Osteoporose bei juveniler idiopathischer Arthritis |
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| Authors: | Dr. J. Roth S. Bechtold G. Borte F. Dressler H. Girschick M. Borte |
| Affiliation: | 1. P?diatrische Pneumologie und Immunologie, SPZ Rheumatologie, Charité Virchow Klinikum, Augustenburger Platz 1, 13353, Berlin, Deutschland 2. Kinderklinik im Dr. von Haunerschen Kinderspital, Klinikum der Universit?t München, München, Deutschland 3. Klinik für Radiologie, Universit?tsklinikum Leipzig, Leipzig, Deutschland 4. Kinderklinik der Medizinischen Hochschule Hannover, Hannover, Deutschland 5. Kinderklinik und Poliklinik, P?diatrische Rheumatologie, Bayrische Julius-Maximilians-Universit?t, Würzburg, Deutschland 6. Klinik für Kinder- und Jugendmedizin, St?dt. Klinikum St. Georg, Leipzig, Deutschland |
| Abstract: | In all subgroups of juvenile idiopathic arthritis (JIA), a pathologic loss of bone or the lack of increase in bone mass has been described in a high percentage of cases, even with new therapeutic approaches. The decrease in bone mass is correlated with the duration of active disease and the number of affected joints (cytokines, inactivity). In several studies, muscle mass was the strongest predictor of bone mass. A standardized diagnostic approach to the musculoskeletal system including measures of prophylaxis and therapy therefore seems to be mandatory for all children with JIA who do not achieve rapid remission. In this review, the diagnostic and therapeutic options are described and summarized in an algorithm. |
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