肾上腺髓质素对肺结核与肺炎鉴别诊断的价值

目的 探讨肾上腺髓质素（AM）对肺结核与肺炎鉴别诊断的价值，为临床早期鉴别肺结核与肺炎提供新的可靠的理论依据。方法 用放射免疫方法分别检测肺结核与肺炎病人及正常对照组血浆中AM的含量，用方差分析进行统计学处理。结果 肺结核与肺炎病人血浆AM含量高于正常对照组（F=30．66，q=11．01、4．44，P〈0．05）；肺结核病人血浆AM含量明显高于肺炎病人（q=6．57，P〈0．05）。结论 AM可作为早期鉴别诊断肺结核与肺炎的实验室指标。

THE VALUE OF ADRENOMEDULLIN IN DIFFERENTIAL DIAGNOSIS BETWEEN PULMONARY TUBERCULOSIS AND PNEUMONIA

Objective To explore the value and clinical significance of adrenomedullin(AM) in differential diagnosis between lung tuberculosis and pneumonia,and to provide a new theoretical basis for early diagnosis of the diseases. Methods The concentration of AM in plasma was measured in 90 persons including patients with lung tuberculosis,pneumonia and normal controls by radioimmunoassay(RIA) method,and the result was analyzed statistically. Results The level of AM in plasma of patients with pulmonary tuberculosis and pneumonia was higher than that of normal controls,the difference was significant(F=(30.66);q=11.01,4.44;P<0.05),and it showed significantly higher in lung tuberculosis patients compared with pneumonia ones(q=6.57,P<0.05). Conclusion AM detection can be used as a laboratory parameter in early differential diagnosis between pulmonary tuberculosis and pneumonia.