常住人口与外来人口肺结核病人耐药性分析

目的　为了解门诊病人中常住人口与外来人口 (以下简称“不同人口”)肺结核病人耐药性的异同。方法 采用绝对浓度间接法,应用改良罗氏培养基对分离菌株进行抗结核药耐药性测定。对不同人口肺结核耐药病例分初、复治两组进行分析。结果 不同人口肺结核病人对常用抗结核药耐药率差别不大,复治病例耐药率明显高于初治病例。两者的初治病例均以耐单药为主、复治病例以耐多药为主。外来人口男、女肺结核病人耐药率均高于常住人口,且外来人口耐药病例比常住人口更年青化。结论 常住人口及外来人口肺结核均处于高耐药状态,须加强结核病耐药性监测。外来人口男、女复治肺结核病患者耐药率都比常住人口高,应引起注意。

The analysis of drug resistance for out-patient pulmonary tuberculosis between resident and migrant

Objective To determine the difference of the dru g resistance of M.tuberculosis between resident TB cases and migrant TB case s from out patient.Methods Absolute concentration method was used for susceptibility test of 5 antituberculosis drugs.Results There was no significant difference on drug resistance rates of those two grou ps. The mostly cases of initial resistance resisted to one drug, and those of acquired resistance resisted to multi drugs. The rate of drug resistance amo ng migrant TB cases was higher than that of the resident TB cases. Conc lusion The rate of drug resistance was high, so we must strengthen surv eillance on antituberculosis drug resistance.