| 隐匿性乙型肝炎病毒感染母婴传播状况的研究 |
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| 引用本文： | 康汉珍,操静,汪晓湘,封秀,贾红,龙霞. 隐匿性乙型肝炎病毒感染母婴传播状况的研究[J]. 护理学杂志, 2009, 24(6). DOI: 10.3870/hlxzz.2009.06.001 |
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| 作者姓名： | 康汉珍 操静 汪晓湘 封秀 贾红 龙霞 |
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| 作者单位： | 北京大学深圳医院妇产科,广东,深圳,518036;北京大学深圳医院妇产科,广东,深圳,518036;北京大学深圳医院妇产科,广东,深圳,518036;北京大学深圳医院妇产科,广东,深圳,518036;北京大学深圳医院妇产科,广东,深圳,518036;北京大学深圳医院妇产科,广东,深圳,518036 |
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| 基金项目： | 深圳市科技信息局立项课题 |
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| 摘 要： | 目的 了解隐匿性乙型肝炎病毒(HBV)感染在孕妇人群中的发生率及母婴传播状况,为制订干预措施提供依据.方法 对 1 000 例血清学检测HBsAg阴性的孕妇进行HBV-DNA检测,阳性者为隐匿性HBV感染,对隐匿性HBV感染孕妇分娩的新生儿进行HBV血清学检测及HBV-DNA检测.统计孕妇人群隐匿性HBV感染的发生率,以及通过母婴传播引起新生儿隐匿性HBV感染的发生率.结果 1 000例HBsAg阴性孕妇中,检测出隐匿性HBV感染病例57例(5.7%),其分娩的新生儿检测出隐匿性HBV感染8例(14.0%).阳性组新生儿母亲HBV-DNA含量显著高于阴性组(P<0.01).结论 孕妇人群中存在一定数量的隐匿性HBV感染,并能通过母婴垂直传播引起胎儿宫内感染;新生儿隐匿性HBV感染的发生率与母亲血清中HBV-DNA含量密切相关.
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| 关 键 词： | 孕妇 新生儿 乙型肝炎病毒 隐匿性感染 母婴传播 血清学检测 HBsAg HBV-DNA检测 |
Status Quo of Maternal-neonatal Transmission of Occult Hepatitis B Virus Infection |
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| KANG Hanzhen,CAO Jing,WANG Xiaoxiang,FENG Xiu,JIA Hong,LONG Xia. Status Quo of Maternal-neonatal Transmission of Occult Hepatitis B Virus Infection[J]. Journal of Nursing Science, 2009, 24(6). DOI: 10.3870/hlxzz.2009.06.001 |
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| Authors: | KANG Hanzhen CAO Jing WANG Xiaoxiang FENG Xiu JIA Hong LONG Xia |
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| Affiliation: | Obstetrics and Gynecology Department;Shenzhen Hospital of Peking University;Shenzhen 518036;China |
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| Abstract: | Objective To explore the rate of occult hepatitis B virus(HBV) infection in pregnant women and the status quo of maternal-neonatal transmission and to provide information for interventional measures.Methods Totally,1 000 HBsAg negative pregnant women were given HBV-DNA detection,and those with positive results were diagnosed as occult HBV infection and their babies received serous HBV and HBV-DNA detection.The incidence rates of occult HBV infection in pregnant women and their newborns were calculated.Resul... |
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| Keywords: | HBsAg |
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