| 丁丙啡用于海洛因依赖的快速戒毒 |
| |
| 引用本文： | 刘志民,王小平.丁丙啡用于海洛因依赖的快速戒毒[J].中国药理学报,1997,18(2):112-114. |
| |
| 作者姓名： | 刘志民 王小平 |
| |
| 作者单位： | [1]北京医科大学中国药物依赖性研究所 [2]西安市碑林戒毒治疗中心 |
| |
| 摘 要： |
|
| 关 键 词： | 物质撤除综合征 丁丙诺啡 海洛因依赖 戒毒药 |
Rapid detoxification of heroin dependence by buprenorphine. |
| |
| Z M Liu,Z J Cai,X P Wang,Y Ge,C M Li.Rapid detoxification of heroin dependence by buprenorphine.[J].Acta Pharmacologica Sinica,1997,18(2):112-114. |
| |
| Authors: | Z M Liu Z J Cai X P Wang Y Ge C M Li |
| |
| Institution: | National Institute on Drug Dependence, Beijing Medical University, China. |
| |
| Abstract: | AIM: To evaluate the clinical efficacy of buprenorphine (Bup) in treatment of acute heroin withdrawal. METHODS: Bup was given sublingually daily to 60 cases of heroin addicts in 3 groups: low, medium, and high doses. Withdrawal signs and symptoms of heroin were rated by Clinical Institute Narcotic Assessment. Craving for heroin during detoxification was assessed by Visual Analogue Scale. The side effects of Bup was assessed by Treatment Emergent Symptom Scale. RESULTS: The mean daily consumption of Bup in low, medium, and high group was 2.0, 2.9, and 3.6 mg, respectively. Bup not only suppressed objective signs and withdrawal symptoms for heroin withdrawal, but also reduced the duration for heroin detoxification over 7-8 d. CONCLUSION: Bup is an effective and rapid detoxification agent with fewer side effects for treatment of acute heroin withdrawal. |
| |
| Keywords: | |
| 本文献已被 维普 等数据库收录！ |
|
