| 序贯疗法在Hp感染性胃溃疡中的应用及吸烟对Hp根除的影响 |
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| 引用本文： | 成雁文.序贯疗法在Hp感染性胃溃疡中的应用及吸烟对Hp根除的影响[J].山西职工医学院学报,2011,21(2):6-8. |
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| 作者姓名： | 成雁文 |
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| 作者单位： | 太原市晋源区妇幼保健所,山西太原,030025 |
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| 摘 要： | 目的：观察序贯疗法治疗胃溃疡（GU）合并幽门螺杆菌（Hp）感染的疗效以及吸烟对Hp根除的影响。方法：选择依靠胃幽门螺杆菌快速检测试纸确诊Hp（＋）的85例患者,分为两组。传统三联疗法组：奥美拉唑20 mg,克拉霉素0.5 g,阿莫西林1 g,均为每天2次;序贯疗法组：前5 d奥美拉唑20 mg,每天2次,阿莫西林1 g,每天2次;后5 d加用克拉霉素500 mg,每天2次,甲硝唑400 mg,每天2次,疗程共10 d。对比两组疗效,并观察两组中吸烟患者对Hp根除的影响。结果：传统三联疗法组溃疡Hp根除率81.0%,序贯疗法组Hp根除率90.7%,两组比较差异有统计学意义。646例吸烟者中治疗时继续吸烟者与戒烟者Hp根除率分别为50.00%和89.47%。结论：序贯疗法根除Hp的效果较好。吸烟可以影响Hp的根除率。
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| 关 键 词： | 胃溃疡 幽门螺杆菌感染 序贯疗法 传统三联疗法 Hp根除率 吸烟 |
Application of Sequential Therapy in Helicobacter Pylori Infective Gastric Ulcer and the Influence of Smoking on Helicobacter Pylori Eradication |
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| CHENG Yanwen.Application of Sequential Therapy in Helicobacter Pylori Infective Gastric Ulcer and the Influence of Smoking on Helicobacter Pylori Eradication[J].Journal of Shanxi Medical College For Continuing Education,2011,21(2):6-8. |
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| Authors: | CHENG Yanwen |
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| Institution: | CHENG Yanwen(Jinyuan District Maternity and Child Care Institute in Taiyuan,Taiyuan 030025,Shanxi,China) |
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| Abstract: | Objective:To observe the curative effect of sequential therapy in treatment of gastric ulcer combined with Helicobacter pylori(Hp) infection and the influence of smoking on Hp eradication.Methods:Eighty-five patients with Hp(+) confirmed by the rapid detection strip of Helicobacter pylori were divided into two groups.The traditional triple-therapy group was treated with Omeprazole 20 mg,Clarithromycin 0.5 g and Amoxicillin 1 g and all were treated twice per day.The sequential therapy group was treated with ... |
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| Keywords: | gastric ulcer Helicobacter pylori infection sequential therapy traditional triple-therapy Hp eradication rate smoking |
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