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Giant Cell Tumor Pulmonary Metastases Mimic Primary Malignant Pulmonary Nodules on 18F-FDG PET/CT
Authors:William Makis  Yazan Z. Alabed  Ayoub Nahal  Javier A. Novales-Diaz  Marc Hickeson
Affiliation:.Department of Nuclear Medicine, Brandon Regional Health Centre, 150 McTavish Ave E, Brandon, MB R7A 2B3 Canada ;.Department of Nuclear Medicine, Royal Victoria Hospital, McGill University Health Centre, 687 Pine Ave West, M2, Montreal, QC H3A 1A1 Canada ;.Department of Pathology, Montreal General Hospital, McGill University Health Centre, 1650 Avenue Cedar, D3-257, Montreal, QC H3G 1A4 Canada
Abstract:A 59-year-old man with a 30-year history of multiple recurrences of a giant cell tumor (GCT) of the left knee was referred for an 18F-FDG PET/CT to evaluate a solitary pulmonary nodule. The nodule was mildly FDG-avid, raising suspicion of malignancy. It was excised and histologically proven to be a GCT pulmonary metastasis. A follow-up PET/CT done 2 years later revealed a new, larger lung mass that was more intensely FDG-avid, but of the same histology. This rare report highlights a pitfall in the evaluation of solitary pulmonary lesions by 18F-FDG PET/CT in patients with GCT of the bone.
Keywords:Giant cell tumor   GCT   Pulmonary metastases   FDG   PET/CT
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