Discovery of MK-7725,
A Potent,Selective Bombesin
Receptor Subtype-3 Agonist for the Treatment of Obesity |
| |
| Authors: | Harry R. Chobanian,Yan Guo,Ping Liu,Marc Chioda,Thomas
J. Lanza,Jr., Linda Chang,Theresa M. Kelly,Yanqing Kan,Oksana Palyha,Xiao-Ming Guan,Donald
J. Marsh,Joseph M. Metzger,Judith N. Gorski,Kate Raustad,Sheng-Ping Wang,Alison
M. Strack,Randy Miller,Jianmei Pang,Maria Madeira,Kathy Lyons,Jasminka Dragovic,Marc
L. Reitman,Ravi P. Nargund,Linus S. Lin |
| |
| Affiliation: | †Departments of Medicinal Chemistry, ‡Metabolic Disorders, §Pharmacology, and ∥Drug Metabolism, Merck Research Laboratories, Rahway, New Jersey 07065, United States |
| |
| Abstract: | | |
| Keywords: | Bombesin receptor subtype-3 BRS-3 agonist obesity benzodiazepine sulfonamide atropisomer MK-7725 |
|
|
