Discovery of SCH 900271,
a Potent Nicotinic Acid Receptor
Agonist for the Treatment of Dyslipidemia |
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| Authors: | Anandan Palani,Ashwin U. Rao,Xiao Chen,Xianhai Huang,Jing Su,Haiqun Tang,Ying Huang,Jun Qin,Dong Xiao,Sylvia Degrado,Michael Sofolarides,Xiaohong Zhu,Zhidan Liu,Brian McKittrick,Wei Zhou,Robert Aslanian,William
J. Greenlee,Mary Senior,Boonlert Cheewatrakoolpong,Hongtao Zhang,Constance Farley,John Cook,Stan Kurowski,Qiu Li,Margaret van Heek,Gangfeng Wang,Yunsheng Hsieh,Fangbiao Li,Scott Greenfeder,Madhu Chintala |
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| Affiliation: | †Department of Medicinal Chemistry, ‡Department of Biology, and §Department of Drug Metabolism & Pharmacokinetics, Merck Research Laboratories, 2015 Galloping Hill Road, Kenilworth, New Jersey 07033, United States |
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| Abstract: | | |
| Keywords: | Nicotinic acid receptor (NAR) agonist flushing dyslipidemia FFA LDL-C VLDL-C TG HDL-C CAD |
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