Increased lymphokine activated killer (LAK) activity in the regional lymph nodes of mice following immunization with contact sensitizing agents. |
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| Authors: | L Q Gao G L Asherson M Malkovsky |
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| Affiliation: | Division of Immunological Medicine, Clinical Research Centre, Harrow, UK. |
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| Abstract: | The regional lymph nodes of mice show increased IL-2 activated killer (LAK) activity following immunization with the contact sensitizing agents, 'oxazolone' and picryl chloride. This is best elicited with 500 mu/ml human recombinant IL-2 and can be demonstrated with both YAC-1 and K562 targets. There is also a lesser increase in NK activity. |
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